Omalizumab in chronic urticaria: A comprehensive review
Journal Title: Türkderm - Deri Hastalıkları ve Frengi Arşivi - Year 2018, Vol 52, Issue 4
Abstract
Omalizumab is a humanized monoclonal anti-immunoglobulin E which is originally developed for the treatment of allergic respiratory disorders, but has been approved for the treatment of antihistamine-resistant chronic spontaneous urticaria in 2014. It has become a game changer in the treatment of all subtypes of chronic urticaria (CU) even though it has not been yet approved for inducible urticarias. It is a safe drug with minor adverse events reported in the clinical trials as well as real life studies. The main questions that remain to be answered regarding its use for CU are the duration of treatment, how to cease the treatment and safety of long-term use. Available information about these questions are tried to be provided in this review.
Authors and Affiliations
Emek Kocatürk Göncü, Kübra Kızıltaç, Tabi Leslie
Keywords
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- EP ID EP427145
- DOI 10.4274/turkderm.26987
- Views 132
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