On Rational Design of Precision Drugs
Journal Title: Open Access Journal of Pharmaceutical Research - Year 2022, Vol 6, Issue 2
Abstract
The rational design of perfect precision drugs must be based on a precise definition of the disease’s molecular target. This article offers a perspective on how the current drug development process needs to change to respond to this demand. This is not a review. However, the article refers to the past drug development to illustrate what needs to be done to progress to the next stage, namely the development of precision drugs–drugs that would act on diseases with no, or at least very much reduced side effects. To this end, unique molecular structures associated with diseases must be identified, followed by developing drugs that would bind specifically to such structures. Finally, future drug development must adopt this new paradigm.
Authors and Affiliations
Petrak K*
Applications and Implications of Viral and Non Viral Vectors in Gene Therapy
Gene therapy is a new technique which uses genes to treat or prevent diseases. Viruses normally possess strong promoters, which can create high level gene expression in the infected host cells. Gene Therapy is recognize...
Comprehensive Review of Phytochemistry and Bioactivities of Citrullus Colocynthis (L.) Schrad
Citrullus colocynthis is a restorative plant which has been used in traditional medicinal systems. Extracts in different solvents are found to possess antibacterial, antifungal, antioxidant, analgesic, hypoglycemic, hyp...
Relationship of Rodents with Corona Viruses Infection- An Overview
Rodents are the most diverse mammals on the planet and are important reservoirs of many pathogens example Coronaviruses infect various animals, but to date, relatively few coronaviruses have been identified in rodents w...
Quantitative Regression Analysis of Total Hardness Related Physicochemical Parameters of Groundwater
Groundwater is the major sources of water for the survival of lives. It is a gift of Mother Nature who supports water to the mankind and animals. Industrialization has been increasing day by day. This is one of the cruc...
Perceived Satisfaction of Public Health Facilities’ with the Quality of Logistics Service Provided by Pharmaceutical Fund and Supply Agency Bahirdar Hub, Northwest Ethiopia: Descriptive Study
Aim: This study aimed to investigate the satisfaction of public health facilities in the quality of logistics services received from the Pharmaceutical Fund and Supply Agency Bahirdar hub. Methodology: A descriptive re...