Oncogenic Osteomalacia: An Approach to Diagnosis with a Case Report
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 4
Abstract
Oncogenic osteomalacia, also known as tumour induced osteomalacia, is a rare paraneoplastic syndrome caused by mesenchymal tumours secreting Fibroblast Growth Factor-23 (FGF-23). The characteristic biochemical findings include hypophosphatemia and low 1,25-dihydroxy vitamin D. The differential diagnosis for hypophosphatemia are varied. We present a case of oncogenic osteomalacia in a 29-year-old female, who presented with complaints of generalized diffuse bone pain and walking difficulty for six months duration. Thus, we have discussed the approach to diagnosis in such a case.
Authors and Affiliations
Biswajit Dey, Debasis Gochhait, Hema Subramanian, Madhusudhanan Ponnusamy
Keywords
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- EP ID EP337748
- DOI 10.7860/JCDR/2017/25055.9634
- Views 102
- Downloads 0
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