One-pot synthesis of spirooxindole derivatives catalyzed by ZnFe2O as a magnetic nanoparticles
Journal Title: Asian Journal of Green Chemistry - Year 2018, Vol 2, Issue 2
Abstract
ZnFe2O4 as a novel nanoparticle was prepared and characterized using x-ray diffraction (XRD) analysis, energy dispersive x-ray (EDX), vibrating sample magnetometry (VSM), and fourier-transform infrared (FTIR) spectra. Then, it is used one-pot three-components synthesis of spirooxindole derivatives via condensation of isatin, malononitrile, and 1,3-dicarbonyl compounds (1,3-cyclohexanedione) under mild reaction conditions in water as a green solvent. The present methodology offers several advantages, including ease of the preparation and handling of the catalyst, simple and easy work-up, short reaction times, high yields of the products and recyclability of the catalyst.
Authors and Affiliations
Hasan Hasani, Mansoureh Irizeh
Keywords
Related Articles
- EP ID EP262439
- DOI 10.22631/ajgc.2017.101002.1025
- Views 89
- Downloads 0
Propargylation of indole under a new dual-site phase-transfer catalyst: A kinetic study
A new multi-site phase-transfer catalyst viz., N,N’-dihexyl-4,4’-bipyridinium dibromide (DSPTC) was synthesized from the low cost starting materials. The structures of the synthesized DSPTC and 1-(prop-2-ynyl)-1H-indole...
Indole derived “turn-on” fluorometric probe for dual detection of Hg2+ and Cu2+ ions at nanomolar level
The newly synthesized 3-(phenyl(phenylthio)methyl)-1H-indole ligand demonstrates chemosensor activity towards environmental and clinically important metal ions viz. Hg2+ and Cu2+, via fluorescence intensity enhancement....
Application of modified sawdust for solid phase extraction, preconcentration and determination of trace lead in water samples
A new sorbent was provided and exerted for separation and preconcentration of Pb (II) before the determination of lead ions by flame atomic absorption spectrometry. The normative studies on extraction, separation and pre...
Microwave-assisted multicomponent reaction for the synthesis of 2-amino-4H-chromene derivatives using ilmenite (FeTiO3) as a magnetic catalyst under solvent-free conditions
A green and highly efficient method has been developed for the synthesis of 2-amino-4H-chromene derivatives in the presence of FeTiO3 as magnetic catalyst via one-pot three-component condensation reaction of aromatic ald...
Imidazole mediated synthesis of spirooxindoles in water using isatin as a privileged scaffold
This work describes the synthesis of complex small molecules spirooxindoles using imidazole as an efficient organocatalyst. The three components coupling reactions of isatin, malononitrile and enolizable 4-hydroxycoumari...