Open Partial Nephrectomy: Results from an 8 Year Study
Journal Title: Archives of Clinical Nephrology - Year 2016, Vol 2, Issue 1
Abstract
Introduction: Nephron sparing surgery is an effective treatment for RCC. Oncological outcome is equivalent to radical nephrectomy, with the added functional advantage. It is underutilized, especially in tumours in anatomically challenging positions like central and hilar positions. Methods: We analyzed the hospital case notes and electronic records of 90 consecutive cases of partial nephrectomies, done at our hospital over the last 8 years. We collected data on the tumours number, size, position (upper zone, central/hilar and lower zone), histology, margin status, operative time, ischemic time, peri-operative complications, length of stay and recurrences so far. We analysed these data according to tumour site (hilar/central vs. polar). Results: 43% of tumours were in the middle zone, 32% lower and 25% upper zone. 81% had elective and 19% imperative indication for nephron sparing surgery. 15% had bilateral tumours. Cold ischemia was used in 40% of the time (20.7 min), warm ischemia in 17% (7.2 min) and no arterial clamping in 43% of the time. The collecting system was opened in 79% of cases. Average operative time was 130 min and length of stay 7.2 days. Complications included, chest infection (4.5%), urinary retention (3.4%), ARF(3.4%), re-operation(2.2%), urinary leak(2.2%) and incisional hernia(5.6%). To date there has been no recurrences or metastatic disease. There was no difference in these results between central/hilar tumours as opposed to upper and lower pole tumours. Conclusion(s): Although may be more technically challenging, nephron sparing surgery for central and hilar tumours is safe and effective.
Authors and Affiliations
Goonewardene S, Shafik A, Chen TF, Makar A
Peritoneal catheter survival: The impact of unroofing
Background: Unroofing is a controversial procedure to avoid catheter removal in the treatment of the chronic exit site and tunnel infection, but is now rarely recommended. Here we aimed to evaluate the effects of the unr...
Steroid Monotherapy for the Treatment for Pure Membranous Lupus Nephritis: A Case Series of 5 Patients and Review of the Literature
Introduction: The benefit of combination immunosuppression versus steroid monotherapy in pure membranous lupus nephritis (MLN) remains unclear. Steroid monotherapy could potentially reduce exposure to excessive immunosup...
ANCA-Associated Vasculitis in Patient with CREST-Syndrome - Case Report
Background: ANCA-associated vasculitis is a small vessel necrotizing vasculitis with few or no immune deposits, necrotizing glomerulonephritis is very common in the microscopic poliangiitis subset. Systemic scleroderma r...
Bioimpedance: Innovative Approach in Nephrology and Autoimmune Diseases
The composition of the human body is considered a useful diagnostic tool in many medical specialties. The recognition of changes in nutrition and hydration of patients is useful in nephrology and in particular in chronic...
Some Aspects of the Evaluation of Brush Border Enzymuria Originating from Proximal Renal Tubules as Screening Test in Patients with Psoriatic Arthritis
Aim: To compare diagnostic values and laboratory variables of alanine - aminopeptidase (microsomale AAP), γ-glutamyl transferase (γ−GT),β2-microglobuline (β2-M), C Reactive Protein (CRP) and index for disease activity (P...