Opisthorchiasis in Northeastern Thailand: Effect of local environment and culture
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2015, Vol 5, Issue 0
Abstract
Opisthorchiasis is a kind of trematode infection. This parasitic infestation is a chronic hepatobiliary tract infection and can cause chronic irritation that will finally lead to cholangiocarcinoma. It is highly endemic in northeastern region of Thailand and contributes to many cholangiocarcinoma cases annually. The attempt to control the disease becomes a national policy. However, the sanitation becomes a major underlying factor leading to infection and meanwhile, the poverty and low education of the local people become an important concern. In this opinion, the authors discuss the effect of local environment and culture on opisthorchiasis in northeastern Thailand. Due to the pattern change of local environment, global warming and globalization, the dynamicity can be observed.
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Molecular docking and binding study of harpagoside and harpagide as novel anti-inflmmatory and antianalgesic compound from Harpagophytum procumbens based on their interactions with COX-2 enzyme
Objective: To clarify the molecular inhibition mechanism of harpagoside and harpagide with cyclooxygenase-2 (COX-2) as natural potent anti-inflammatory and anti-analgestic compounds derived from the Harpagophytum species...
Phytochemical screening and evaluation of anti-inflammatory activity of methanolic extract ofAbroma augusta Linn
Objective: To evaluate the Phytochemical and anti-inflammatory property of the different parts of methanolic extracts of Abroma augusta Linn. Materials and methods: Abroma augusta Linn (Family-Malvaceae) commonly known a...