Opportunistic and other intestinal parasites infections among HIV-positive patients in the era of combination antiretroviral therapy and preventive treatment in Ouagadougou, Burkina Faso
Journal Title: Journal of HIV for Clinical and Scientific Research - Year 2017, Vol 4, Issue 2
Abstract
Background: One of the particularities of human immunodeficiency virus (HIV) infection in the tropics is its frequent association with parasitic diseases so frequent in this area. Aim: The aim of this study was to update the epidemiological and clinical profile of intestinal parasites among HIV-positive patients in the era of combination antiretroviral therapy (ART) and preventive treatment in Ouagadougou, Burkina Faso. Materials and Methods: A cross-sectional study was conducted in a single health care system, Yalgado Ouédraogo University hospital, between January 2013 and December 2014. A total of 131 HIV-infected patients were included in the study. Blood and Stool samples were collected for CD4 counts and for intestinal parasitic examination using direct, formol-ether concentration, a concentration method using sodium chloride solution, modified Ziehl-Neelsen and Weber modified trichrome. Odds ratio was calculated to estimate the risk attributable to different factors with confidence intervals. Chi-square (X2) or Fisher’s Exact Test statistical analysis was used to test level of significance at p<0.05 using SPSS 20.0.0. Results: A prevalence of 73.3% of intestinal parasites was recorded. Most of the parasitic infections were protozoa (97.9%) with few helminths (2.1%). Cryptosporidium spp. (29.2%), was the most commonly found parasite followed by Entamoeba coli (23.9%) and Isospora belli (21.9%). There were 76 cases (78.5%) of single infection and 20 cases (21.5%) of mixed infection. Paradoxically, patients who use preventive treatment were more infected with opportunistic parasites (p= 0.05, OR=2.16, 95% CI= 1.06-4.40). In multivariate analysis, patients with diarrhea (OR=4.04, 95% CI=1.94-8.41), and illiterate (OR=3.70, 95% CI=1.68-8.14) had higher risk of opportunistic parasites. The diarrheic patients were 0.29 times more likely to be infected with opportunistic parasites. Conclusion: Despite the advent of combination ART and preventive treatment of opportunistic infections, intestinal parasites remain very prevalent and associated with diarrhea among patients with HIV in Ouagadougou.
Authors and Affiliations
Zida Adama, Yacouba Abdourahamane, Sawadogo Marcel P, Diallo Ismael, Sangare Ibrahim, Bamba Sanata, Ouattara Bassory, Guiguemde Tinga R
Keywords
Related Articles
- EP ID EP348132
- DOI 10.17352/2455-3786.000022
- Views 81
- Downloads 0
Care burden derived from the introduction of an early Lung Cancer Screening Program in high risk HIV-infected patients
We describe the care burden derived of a lung cancer screening program in HIV high risk patients. In a well selected group with the described criteria, one annual low-dose thoracic computed tomographic exploration can be...
Adherence to Early Infant Diagnosis Testing Algorithm, a Challenge to Early Infant Diagnosis Program in Resource Limited Settings of Uganda
Introduction: Early Infant Diagnosis (EID) targeting HIV exposed infants, happens over a period of time (6 weeks up to 18months), and employs different testing technologies at different testing time points. Being a proce...
Opportunistic and other intestinal parasites infections among HIV-positive patients in the era of combination antiretroviral therapy and preventive treatment in Ouagadougou, Burkina Faso
Background: One of the particularities of human immunodeficiency virus (HIV) infection in the tropics is its frequent association with parasitic diseases so frequent in this area. Aim: The aim of this study was to update...
Burden of HIV Infection in Children with Severe Acute Malnutrition at the University of Abuja Teaching Hospital Gwagwalada, Nigeria
Background: Human Immunodeficiency Virus pandemic has adversely affected the nutritional status of many children in the sub region, an area where malnutrition is also endemic. The study was aimed at assessing the burden...
Oral Health Status and Anthropometric Conditions among HIV Infected Adolescents on Antiretroviral Therapy in Mozambique
Background: Malnutrition and weight loss are important characteristics in HIV/AIDS patients. The association between this type of pathology and oral health in HIV/AIDS patients maintains unclear in the literature. Object...