Optical coherence tomography angiography of optic disc perfusion in non-arteritic anterior ischemic optic neuropathy
Journal Title: International Journal of Ophthalmology - Year 2017, Vol 10, Issue 9
Abstract
"AIM: To compare the optic disc blood flow of non-arteritic ischemic optic neuropathy (NAION) eyes with normal eyes. METHODS: The optic disc blood flow densities of diagnosed non-acute phase NAION eyes (21 eyes, 14 individuals) and normal eyes (19 eyes, 12 individuals) were detected via Optovue optical coherence tomography angiography (OCTA). The optic disc blood flow was measured via Image J software. Correlations between optic disc perfusion and visual function variables were assessed by linear regression analysis. RESULTS: The average percentage of the optic disc non-perfusion areas in the non-acute phase NAION patients (17.84%±6.18%) was increased, when compared to the normal control eyes (8.61%±1.65%), and the difference was statistically significant (P<0.01). Moreover, there was a proportional correlation between the visual field mean defect (MD) and the optic disc non-perfusion area percentage, and the relationship was statistically significant (t=3.65, P<0.01, R2=0.4118). In addition, the critical correlation between the best corrected visual acuity (BCVA) and the optic disc non-perfusion area percentage was statistically significant (t=4.32, P<0.01, R2=0.4957). CONCLUSION: The optic disc non-perfusion area percentages detected via OCTA in NAION eyes were significantly increased when compared with the normal eyes. Both the BCVA and MD were correlated with the optic disc flow detected, revealing that OCTA may be valuable in the diagnosis and estimation of NAION."
Authors and Affiliations
Pei-Rong Lu
Keywords
Related Articles
- EP ID EP594604
- DOI 10.18240/ijo.2017.09.12
- Views 56
- Downloads 0
Change in foveal position based on age and axial length in high myopic eyes
"AIM: To evaluate the influence of age and axial length (AL) on the position of the fovea in patients with high myopia (HM). METHODS: In this prospective study, 96 patients (186 eyes) with HM were consecutively recruited...
Comment on “Management strategies in malignant glaucoma secondary to antiglaucoma surgery”
Comment and Response
Comparison of persistent submacular fluid in different preoperative macular status after vitrectomy for rhegmatogenous retinal detachment
"AIM: To compare the incidence of persistent submacular fluid (SMF) and visual outcome after pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD) in different preoperative macular status according to o...
Multimodal imaging of the carriers of choroideremia and X-linked retinitis pigmentosa
Letter to the editor
Effects of lens extirpation with anterior vitrectomy on vitreous three-dimensional mesh structure
"AIM: To investigate the changes in vitreous gel structure after lens extirpation combined with anterior vitrectomy in rabbit eyes. METHODS: Twenty-eight chinchilla rabbits were divided into three groups. The control gro...