Optimisaton techniques: a futuristic approach for formulating and processing of pharmaceuticals
Journal Title: Indian Journal of Pharmaceutical and Biological Research - Year 2016, Vol 4, Issue 2
Abstract
Designing and formulating an ideal pharmaceutical product is a very tedious job for a formulator as it comprises of multiple objectives. The traditional method followed for years is not only expensive and time consuming but it also needs lot of effort to be put in and in spite of that at times it proves to be unfavourable and unpredictable too.The recent approach to optimise i.e. to achieve the best combination of product and process characteristics under the given conditions is by using Design of Experiment (DoE).Design of Experiment (DoE) is an organised approach to determine the relationship between the factors (Xs) affecting a process and the output of that process (Ys).The recent optimisation methodologies include various approaches that come under the 2 main categories namely, simultaneous optimisation and sequential optimisation. Nowadays there are various software available to carry out the optimisation of pharmaceutical products.
Authors and Affiliations
REHA S. CHODANKAR| Department of Pharmaceutics, Oriental College of Pharmacy, Sanpada, Navi Mumbai,India, ASISH DEV| Department of Pharmaceutics, Oriental College of Pharmacy, Sanpada, Navi Mumbai,India
Keywords
Related Articles
- EP ID EP15501
- DOI -
- Views 349
- Downloads 17
Evaluaton of hypoglycaemic activity of Aegel marmelos alcoholic seed extract in experimental models of hyperglycemic rats
The present study aimed to investigate the antidiabetic effect of alcoholic seed extract of Aegel marmelos in comparison with glibenclamide in in vivo using alloxan rat model.The diabetic rats were orally given glibenc...
Neuroprotective Effect of Cinamomum zeylanicum in streptozotocin induced diabetes in Mice
Background: Diabetes is recognized as one of the leading causes of morbidity and mortality & representing as an emerging global epidemic worldwide. Diabetes and stroke both are the conditions which share various common t...
Proximate Composition And Phytochemical Constituents Of Aspilia africana (Pers) C. D. Adams & Tithonia diversifolia (Hemsl) A. Gray Stems (Asteraceae)
Proximate composition and phytochemical constituents of stems of A. africana and T. diversifolia (Asteraceae) were investigated. The stems of these species contain anti-oxidant, anticancer, anti-tumor, anti-viral, anti...
A Randomised Controlled Trial Comparing Intravaginal Misoprostol and Intracervical Dinoprostone in Pre Induction Cervical Ripening
Objective: To compare the efficacy and safety of intravaginal misoprostol with intracervical dinoprostone for preinduction cervical ripening. Material &Methods: It was a randomized controlled trial conducted at departme...
Emulgel: Magnifying the application of topical drug delivery
Topical drug delivery is mostly culled for the local dermatological action, but recently the new technologies are also enhancing its systemic effect. They are generally applied for the purpose as antiseptics, antifungal...