Optimization of Water Based-extraction Methods for the Preparation of Bioactive-rich Ginger Extract Using Response Surface Methodology
Journal Title: European Journal of Medicinal Plants - Year 2014, Vol 4, Issue 8
Abstract
Aims: Evaluation of three extraction methods to prepare bioactive-rich ginger extract for incorporation into a functional beverage. Study Design: Response surface methodology. Methodology: For the preparation of bioactive-rich ginger extract with water, conventional hot water extraction, ultrasonic-assisted extraction and high pressure homogenization-assisted extraction were evaluated. Response surface methodology was employed to optimize the extraction conditions of each method with respect to the highest polyphenols, antioxidant capacity (ferric reducing antioxidant power; FRAP) and percent inhibition of low density lipoprotein (LDL) cholesterol oxidation. Results: Multiple response optimizations revealed that the optimum extraction conditions for each extraction method were 60min extraction time under 55°C for hot water extraction, 15min ultrasonication under 52°C for ultrasonic-assisted extraction and 62°C under 140MPa homogenization pressure for high pressure homogenization-assisted extraction. Conclusion: The extract prepared from the ultrasonic-assisted extraction method exhibited the highest polyphenol recovery and antioxidant activity, compared to the extracts prepared from other two methods.
Authors and Affiliations
K. D. P. P. Gunathilake, H. P. Vasantha Rupasinghe
Keywords
Related Articles
- EP ID EP350016
- DOI 10.9734/EJMP/2014/10322
- Views 137
- Downloads 0
Evaluation of Commonly Used Surinamese Medicinal Plants for Their Potential Cytotoxic and Genotoxic Effects Using Cultured Chinese Hamster Ovary Cells
Aim: There are often no records about the potential toxicities of medicinal plants including their possible adverse maternal and perinatal effects. In this study, a number of commonly used plant-derived traditional prepa...
In vitro Antiplasmodial and Antioxidant Activities of Entandrophragma cylindricum (Meliaceae) Extracts
Malaria is still regarded as a major global infectious disease in the 21st Century with a high pediatric mortality toll in the developing world. In Africa, malaria is one of the diseases causing the most morbidity and mo...
Anti-inflammatory Activity of Leaf Extract and Fractions of Tapinanthus bangwensis (Engl. & K.Krause) Danser Parasitic on Citrus angustifolia
Aim: This study was undertaken to evaluate the anti-inflammatory activity of extract of the leaves of the plant. Study Design: The study adopted the experimental design. Place and Duration of Study: Department of Pharmac...
Neuropharmacological Activities of Ethanolic Extract of Cola millenii Dried Leaf in Rats
Objective: The leaf of Cola millenii is used in ethnomedicine to treat several ailments including; infections, fever and pain among several other diseases in Southwest Nigeria. Preliminary report indicates that the ethan...
A Preliminary Ethno-medical Survey of Plants Used in the Traditional Management of Cancer and Related Diseases amongst Tarok People of Plateau State, North-Central Nigeria
Aim of the Study: To document medicinal plant used in the treatment of cancer and related diseases amongst Tarok people of Plateau State, North-Central Nigeria. Study Design: Ethno medical survey and medicinal plant docu...