Oral manifestations arising from antineoplastic therapy in child oncological patients
Journal Title: Revista Uningá - Year 2021, Vol 58, Issue 1
Abstract
In Brazil, cancer is the leading cause of death from illness in children and adolescents. The National Cancer Institute (INCA) estimates the occurrence of 8,460 new cases of cancer in children and adolescents in 2020. The objective of this study was to identify the most frequent oral manifestations in pediatric patients undergoing antineoplastic treatment. This survey included 137 children and adolescents from 0 to 18 years of age. The data included a semi-structured questionnaire to verify the most frequent oral manifestations resulting from antineoplastic therapy. The statistical tests used were the Pearson's Chi-square test and to assess the strength of the association, Odds Ratio (OR) or Ratio of Chances (RC) with respective confidence interval was obtained. The results found showed that the average age of the patients surveyed was 6.8 years; the male gender (57.7%) was predominant in the sample; the most frequent malignancy was leukemia (67.9%); 70.1% of patients had at least one oral manifestation, with mucositis being the most prevalent (56.2%), followed by dry mouth (46.7%), gingivitis (41.6%), dysphagia (35.8%), dysgeusia (35.8%), candidiasis (34.3%) and herpes (21.2%). There were 54.7% of patients with favorable oral health and 40.9% of them with unfavorable oral health. We conclude that the infant patient should be evaluated by a pediatric dentist prior to the start of chemotherapy to minimize oral complications during antineoplastic treatment.
Authors and Affiliations
Híttalo Carlos Rodrigues Almeida, Mabel Cristina Paiva Machado Silva, Maria Carlla Aroucha Lyra, Maria Cristina Valença de Oliveira, Fabiana Moura da Motta Silveira, Rebeca Luiz de Freitas, Ana Paula Veras Sobral.
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