Oral misoprostol for cervical ripening prior to surgical termination of pregnancy (MTP)
Journal Title: MedPulse -International Medical Journal - Year 2015, Vol 2, Issue 1
Abstract
Objective: To evaluate the efficacy of misoprostol as an adjunct to manual vacuum aspiration in termination of pregnancy of 6-12 weeks with previous caesarean section. Method: During the study period of 2 years from January 2013 to December 2014, 50 healthy pregnant women with 6-12 weeks gestation and a history of previous one caesarean section were randomly assigned in two groups of 25 subjects each. Group I received 400 µg of misoprostol at bed time for preoperative cervical priming and were asked to attend next morning pregnancy termination. Group II formed the control and did not receive any preoperative cervical priming. Main outcomes studied were cervical dilatation were evaluated. Results: Just prior to the surgical procedure the mean cervical dilation in group I was 6.5 mm and in Group II was 3.8 mm. Mean blood loass in Group I was 30 ml and in Group II 72 ml. the time required for the surgical procedure in Group I was 4 minutes and in Group II 6.8 minutes. Pain and bleeding occurred in seven patients in Gourp I. Conclusion: Misoprostol as an adjunct to manual vacuum aspiration in patients with previous cesarean section at 6-12 weeks of gestation was safe and cost effective. But it should be used with strict vigilance and monitoring.
Authors and Affiliations
Jyotsna R Himgire, Meenal Vardhan
Keywords
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