Orally disintegrating tablets: A novel approach for medication
Journal Title: International Journal of Medical and Health Research - Year 2019, Vol 5, Issue 1
Abstract
An orally disintegrating tablet (ODT) is a drug dosage form available for a limited range of over-the counter (OTC) and prescription medications. Orally disintegrating tablets differ from the traditional tablets, in that they are designed to be dissolved on the tongue rather than swallowed whole. This article quotes the advantages of orally disintegrating tablets (ODTs) as well as critical issues during evaluation of ODTs such as bioequivalence and challenges and limitations of ODTs and finally present and the future of ODTs. ODTs have received ever increasing demand and this particular field has become a rapidly growing area in the pharmaceutical industry. By introducing into the mouth, these tablets dissolve or disintegrate in the mouth in the absence of additional water. When ODTs are put on tongue they disintegrate instantly, releasing the drug which dissolve or disperse in the saliva fluid. Some drugs are absorbed from the mouth, pharynx and oesophagus as the saliva passes down in the stomach. In such cases, bioavailability of the drug is significantly greater than those observed from the conventional tablet dosage form. The advantages of the mouth dissolving dosage form are increasingly being recognized in both, industry and academia. Their growing importance has been underlined recently when European Pharmacopoeia adopted the term “Orodispersible Tablet” as tablet that is to be place in the mouth where it disperses rapidly before swallowing. ODTs have some challenges and if we implement the use of herbal ingredients in that it would be more challenging but solutions to overcome these challenges were shown in this paper.
Authors and Affiliations
Pawan Kumar Rai, Kinjal Modi
Keywords
Related Articles
- EP ID EP581868
- DOI -
- Views 166
- Downloads 0
Assessment of stapes-pyramidal fixation by a bony bar
Symmetrical hearing loss averaging 30-60 dB (0-125-8 kHz) became apparent between 8 and 24 years of age. Tympanotomy showed a fixed stapes either through ossified stapedius tendon or through a bony bridge from the stapes...
Study of fatty liver disease
There are hardly any studies to assess the prevalence in the rural regions of India. This study aims at assessing the prevalence of disease in rural areas of north India by targeting a small rural sector from north India...
An observation of the immediate outcome of the asphyxiated neonates with myocardial impairment
This was an observational prospective experimental study was conducted in Dhaka Shishu Hospital (DSH) from July 2015 to June 2017. Our aim was to Immediate Outcome of the Asphyxiated Neonates with Myocardial Impairment....
Assessment of the accessibility of oral health care of Senegalese households
Background: Access to health care in general and oral care in particular, is an issue in most developing countries, which contributes to a significant economic burden. The impact of dental pain limits daily activities an...
A study on hepatitis-B in pregnant women and their neonatal outcome
Chronic hepatitis B virus (HBV) infection remains an important worldwide cause of chronic liver disease, which may lead to the development of cirrhosis, decompensated liver disease, and/or hepatocellular carcinoma. It is...