Original Research Article - Etiology, clinical features and outcome of status epilepticus at a tertiary care hospital in Nepal
Journal Title: International Journal of Medical and Health Research - Year 2017, Vol 3, Issue 10
Abstract
Objective: Our study was to evaluate the demographic and clinical characteristics, establish etiological spectrum and outcome of patients with status epilepticus. Methodology: A total of 80 patients with status epilepticus were enrolled in this study. A detail clinical history and examinations were taken to all patients. Uday Pareek Scale was used to know the socioeconomic status. Patient’s vital parameters such as pulse rate, blood pressure, temperature, and respiratory rate were also noted. Neurological assessment was also performed such as GCS, cranial nerve examination including fundoscopy, motor examination, meningeal signs, and cerebellar sign. The duration, type and frequency of seizures at presentation were determined as per detailed interview of eyewitness and/or accompanying person. All patients were treated according to the standard guidelines, clinician’s judgment and the availability of drugs. Drug of choice were phenytoin, diazepam and sodium valproate. Results: Data was analyzed by using statistical methods. Mean ± standard deviation was calculated and p value was taken less than 0.05 for significant differences. Conclusions: Patients with middle socioeconomic status and young age group were more affected with SE. Neurocysticercosis and CNS infection was commonest causes of SE. Poor drug compliance was commonest precipitating factor and convulsive status epilepticus was commonest type of SE. Independent predictors of death in SE were low GCS (<8) at presentation, use of second line drug and respiratory failure.
Authors and Affiliations
Dr. Atul Baid
Keywords
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