Osteoclasts: Multifaceted Molecule in Vesicular Trafficking
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 8
Abstract
ABSTRACT It has been widely accepted that periodontitis is a result of the host immune inflammatory response caused by various periodontal microorganisms leading to tissue degradation and bone resorption. One important mechanism of the inflammatory mediators present in periodontal tissue is the stimulation and formation of osteoclasts that are believed to be the major cell type responsible for bone resorption. This review article comprehensively explains the various molecular activities of osteoclasts and their role in periodontitis.
Authors and Affiliations
Anil Kumar Kanakamedala, Jaideep Mahendra, Nashra Kareem, Little Mahendra
Keywords
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- EP ID EP639003
- DOI 10.7860/JCDR/2019/40307.13064
- Views 117
- Downloads 0
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