Osteopoikilosis: a case report and literature review
Journal Title: Scholars Journal of Medical Case Reports - Year 2017, Vol 5, Issue 4
Abstract
Abstract: Osteopoikilosis (OPK) is a rare, benign, autosomal dominant disorder, in which sclerotic bone lesions could be found all over the skeleton. Patients are usually asymptomatic; lots of them are discovered incidentally on radiographic images. Loss of-function mutations in LEMD3 gene may be responsible for the lesions. The main differential diagnosis in OPK are mastocytosis, tuberous sclerosis and, osteoblastic metastasis. Bone scintigraphy plays a crucial role in distinguishing OPK from malignant diseases. Since there might be an association between osteopoikilosis and osteosarcoma, clinical follow-up is necessary. Keywords: Osteopoikilosis; autosomal dominant; sclerotic; skeleton
Authors and Affiliations
Yangliang Huang, Houqing Long
Keywords
Related Articles
- EP ID EP380588
- DOI -
- Views 78
- Downloads 0
Primary Hepatic Hydatid Cysts: Case Reports
Particularly common in countries with extensive agriculture and livestock, hydatid cyst is a parasitic disease caused by the cestode Echinococcus granulosus, which infects humanmostly through dog faeces. Among the genus...
Human Rights Abuse: Hideous Bite of a Woman by her Husband following a Sexual Assault
Bite of wives by their husbands is non common in partner violence in Mali. Violence against women is growing worldwide. It may be a pitfall for husbands since they can be prosecuted in case their wives report them to the...
A Soujourn beyond Palliation of Stage 4 Ovarian Cancer: Case II
This case report describes a patient diagnosed to have advanced Stage 4 Ovarian cancer malignancy on first visit during May 2015.Three major hospitals in Chennai had declared the case as inoperable and suggested only pal...
Comprehensive Management of Recurrent Bilateral Auricular Keloids: A Case Report
Keloids are aberrations in the wound healing process characterized by formation of a nodular hypertophic lesion which is formed as a result of imbalance in anabolic and catabolic processes. Pressure therapy in combinatio...
Amelanotic Melanoma of the Rectum: A Rare Case Report
Malignant melanoma accounts for 15% of the primary malignant tumors of the anorectal region. However, upto one-third of the anorectal melanomas are amelanotic and cause diagnostic challenges. They are often mistaken for...