Outcomes Assessment of Transoral Laser Microsurgery for T1 and T2 Glottic Cancer at the Ho Chi Minh City Ear-Nose-Throat Hospital
Journal Title: Journal of Clinical and Diagnostic Research - Year 2018, Vol 12, Issue 6
Abstract
ABSTRACT Introduction: Transoral Laser Microsurgery (TLM) has been accepted as a major treatment modality for early glottic carcinoma (T1, T2), with well-known advantages over Radiation Therapy (RT) and open partial laryngectomy. Aim: To evaluate the oncological outcomes in a consecutive series of early glottic carcinomas treated with TLM as a singlemodality therapy. Materials and Methods: The study was conducted using the medical records of 32 consecutive patients who underwent TLMs and postoperative follow-ups. We only evaluated the oncological outcomes for 1-year disease-free survival and the organ preservation rate. The prognostic values of the related clinicopathological factors were evaluated using univariate analysis. Results: Of the 32 patients, 31 were males and one was a female, with an average age of 61 years. The tumours were treated by cordectomy types IV (78.1%), Va (18.8%) and Vb (3.3%). The voice outcomes were assessed using the Voice Handicap Index scale, which showed that 8 patients had normal voices and 22 had mild changes. Only 2 had moderateto- severe voice changes. The mean hospitalization period was 4.4 days (range 3-7 days). For resection margins, as reported by the pathologist, 31 cases (96.9%) had negative margins and 1 case (3.1%) had a positive margin. Conclusion: Laser surgery has very good oncological outcomes for T1 and T2 glottic cancer with the highly proportion of negative margins and the voice outcomes is normal or mild changed.
Authors and Affiliations
Thuy Phan Chung Tran, Tuan Thanh Nguyen
Keywords
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- EP ID EP541846
- DOI 10.7860/JCDR/2018/36675.11710
- Views 51
- Downloads 0
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