Outcomes of accelerated corneal collagen cross-linking in keratoconus

Journal Title: Офтальмологический журнал - Year 2018, Vol 0, Issue 3

Abstract

Keratoconus (KC) is a degenerative noninflammatory disease of the cornea which is characterized be structural changes in the cornea which leads to progressive thinning and bulging in the central and/or peripheral part of the cornea and is accompanied by irregular astigmatism and significant vision impairment. Today, keratoconus treatment is focused on a stage of disease development. At progressive KC stages (II-III), corneal collagen cross-linking is performed. At the present, a latest-generation unit (UV-X™2000, Avedro) is used to perform accelerated cross-linking, which allows for a threefold decrease of the procedure duration (to 10 minutes) compared to the standard protocol Material and Methods. Corneal collagen cross-linking was performed in 71 patients (100 eyes). Results. Accelerated corneal collagen cross-linking for keratoconus stages II-III made it possible to stabilize the pathological process in 100% of cases, based on 12 month follow-up. Keratoconus stabilization was accompanied by: a decrease of astigmatism by 1.4 D and of the corneal refractive power by 3.2D; an increase of the corneal thickness by 8.8 nm; an increase of UCVA and BCVA in 96.5% and 89.6% of cases, respectively; and recovery of normal corneal architectonics according to confocal biomicroscopy data. Subjectively, 64 patients (90%) noted the improvement in the vision quality and better tolerance to spectacles correction.

Authors and Affiliations

G. Drozhzhyna, L. Troychenko, V. A. Naumenko, O. Ivanova, E. Sereda

Keywords

Related Articles

Correlation between axial length and anterior chamber depth of the eye and retinal disorders in type 2 diabetic rabbits with myopia

Background. Recently, a protective effect of high myopia on the retina in diabetes has been reported; however, the mechanism of the interrelation between the elongation of axial length and the severity of diabetic compli...

Report on Filatov Memorial Lectures – 2019, the Research-to-Practice Conference

Filatov Memorial Lectures-2019, a research-to-practice conference with international participation, was held in Odesa on the 23rd -24th of May 2019. The event was organized by SI “The Filatov Institute of Eye Diseases a...

Comparing bioelectrical activity of the peripheral retina among myopic patients operated for rhegmatogenous retinal detachment complicated by choroidal detachment

Background: High myopia is known to be a major risk factor for the development of choroidal detachment (CD) in eyes with rhegmatogenous retinal detachment (RRD). Trophic disturbances of the retina in axial myopia have be...

Results of vitreous surgery with 20% C3F8/air mixture for macular holes larger than 800 μm

Background: Vitreous surgery for large macular holes is still a challenge to the ophthalmologist. Purpose: To assess the efficacy of the 20% C3F8/air mixture in the vitrectomy surgery for macular holes > 800 μm in diame...

Mathematical analysis of the effect of Pro72Arg polymorphism in the TP53 gene on the emergence and progression of POAG

Background: Elevated intraocular pressure (IOP) is a major risk factor for primary open-angle glaucoma (POAG). Increased attention is also given to activation of apoptosis of retinal ganglion cells which results in the d...

Download PDF file
  • EP ID EP423381
  • DOI 10.31288/oftalmolzh201831016
  • Views 109
  • Downloads 0

How To Cite

G. Drozhzhyna, L. Troychenko, V. A. Naumenko, O. Ivanova, E. Sereda (2018). Outcomes of accelerated corneal collagen cross-linking in keratoconus. Офтальмологический журнал, 0(3), 10-16. https://europub.co.uk/articles/-A-423381