Outcomes of Intravitreal Dexamethasone Implant in Persistent Macular Edema Due to Retinal Vascular Diseases Intravitreal Dexamethasone Implant in Persistent Macular Edema
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 10
Abstract
Purpose: To evaluate the safety and efficacy of intravitreal Dexamethasone implant in patients with persistent macular edema due to retinal vascular diseases. Methods: This retrospective analysis was done after intravitreal injections of 0.7mg Dexamethasone implant Ozurdex in 22 eyes of 21 patients with persistent macular edema due to retinal vascular diseases either after at least one anti-VEGF intravitreal injection or photocoagulation from April 2015 to March 2016. Best corrected visual acuity (BCVA) was assessed through Snellen’s chart, and converted to logMar scale. Central macular thickness (CMT) was measured by Spectral-Domain Optical Coherence Tomography (SD-OCT). BCVA, Intraocular pressure (IOP) and CMT was noted at baseline (M0) and repeated after one month, three months, four months, and six months post injection. Results: The average thickness of the retina at baseline was 652𝜇m, the median BCVA was 0.8 logMAR, and corrected intraocular pressure was 12.8 mmHg. The maximum decrease in mean retinal thickness was observed at four weeks following the treatment and was 298𝜇m, and visual acuity improved by an average of four lines and was 0.4logMAR. No complications were observed during the follow-up. Conclusion: Intravitreal Dexamethasone implant appears effective in management of persistent macular edema due to retinal vascular disease with high safety level.
Authors and Affiliations
Arunava kundu, Debabrata datta, Sneha batra, Aniket ginodia, Preeyam biswas, Partha biswas
Keywords
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- EP ID EP244875
- DOI 10.9790/0853-1610157882
- Views 63
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