Abstract

There has been a global interest worldwide in the recent trend of medical researches, which is basically a merge up between basic biology and engineering tools/technology. Imaging, microfluidics, nanofluidics, surface plasmon resonance (SPR) sensor systems, etc. are the widely used engineering tools in medical researches and has given effective clinical results. The most effective and widely used technology amongst these would be nanotechnology which employs methods like nano drug delivery, nano detection of tumors, assay methods, to detect tumor cells, reach the desired target and kill the tumors. This article lays an insight into the application of nanotechnology to treat ovarian cancer by suicide gene therapy, where in the most promising outcome was delivery of DT-A (Diphtheria toxin suicide protein) encoding DNA with transcriptional regulation targeting tumor cells and gene expression in the ovarian region.

Authors and Affiliations