Ovarian Masses: Hitting the Oncological Dart with Ultrasound and CT - A Comparative Study in a Remote Northeast Indian Town
Journal Title: International Journal of Anatomy Radiology and Surgery - Year 2017, Vol 6, Issue 2
Abstract
Introduction: Ovarian cancer is the second most common gynecological malignancy in Indian women after cervical carcinoma. It is a giant killer with the worst prognosis amongst all gynecological malignancies, primarily due to late diagnosis. Therefore, radiological evaluation of ovarian masses is pivotal in making early diagnosis and lesion characterization thereby determining the therapeutic approach. Aim: To assess the individual and relative role of Ultrasonography (USG) and Computed Tomography (CT) in evaluation of benignity and malignancy of ovarian masses with pathological correlation. Materials and Methods: After approval from Institutional Ethical Committee, a prospective study was conducted in the Department of Radiology, Assam Medical College and Hospital, Dibrugarh, India for duration of 1 year from June 2013 to May 2014. Total 52 patients with clinically suspected ovarian masses were evaluated by USG and CT. Pathological evaluation was taken as gold standard. Sensitivity, specificity and diagnostic accuracy of both modalities in determining benignity and malignancy were calculated. Kappa value was used for assessing inter modality agreement on various parameters. Final results were compared by Chi-square test. Results: USG showed 76.43% sensitivity, 83.33% specificity and 78.85 accuracy. CT showed 91.17% sensitivity, 77.77% specificity and 86.53% accuracy. Two tailed p-value for USG and CT calculated by Chi-square test was 0.1133; marking a statistically insignificant association. Conclusion: USG should be the primary modality to evaluate a suspected ovarian mass pertaining to its high specificity in delineating benign from malignant masses, a high morphological sensitivity for the lesion and the lack of radiation. In a suspicious lesion, CT is advised as second modality for its high sensitivity for malignancy and its associated features.
Authors and Affiliations
Manali Arora, Vishal Dhirenbhai Thakker, Geetika Sindhwani, Rudra Kant Gogoi
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