Overview of Congenital, Senile and Metabolic Cataract
Journal Title: Journal of Ocular Biology - Year 2015, Vol 3, Issue 2
Abstract
Opacity of the lens is a major public health problem of unknown causes and impaired vision of a large number of peoples. There are different forms of cataractous lenses including congenital, senile and metabolic associated ones. Although the congenital and senile cataractous lenses were markedly different in its origin, developmental aspects and genes involved, the patho-physiological pathways seemed to be similar. The present review summarized the causes of cataractous lenses such as genetic and abnormal conformational changes of glycation end products. The alterations of proteins, lipids, minerals and antioxidants defense were illustrated and discussed.
Authors and Affiliations
Hassan I El-Sayyad
Keywords
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- EP ID EP197813
- DOI 10.13188/2334-2838.1000023
- Views 115
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