Overview of Congenital, Senile and Metabolic Cataract
Journal Title: Journal of Ocular Biology - Year 2015, Vol 3, Issue 2
Abstract
Opacity of the lens is a major public health problem of unknown causes and impaired vision of a large number of peoples. There are different forms of cataractous lenses including congenital, senile and metabolic associated ones. Although the congenital and senile cataractous lenses were markedly different in its origin, developmental aspects and genes involved, the patho-physiological pathways seemed to be similar. The present review summarized the causes of cataractous lenses such as genetic and abnormal conformational changes of glycation end products. The alterations of proteins, lipids, minerals and antioxidants defense were illustrated and discussed.
Authors and Affiliations
Hassan I El-Sayyad
Keywords
Related Articles
- EP ID EP197813
- DOI 10.13188/2334-2838.1000023
- Views 110
- Downloads 0
Levels of Plasma Homocysteine,Serum Vitamin B12 and Folic Acid in Primary Open Angle Glaucoma - A Case Control Study
Purpose: To study the levels of Plasma homocysteine and serum vitamin B12 and folic acid in cases of Primary Open Angle Glaucoma(POAG). Methods: It was a case-control cross sectional observational study for duration of...
Massive Extraorbital Extension in a Recurring Untreated Retinoblastoma: A Rare Case from Lebanon
Orbital retinoblastoma usually carries a dismal prognosis. We describe a case of a 2 year old boy with a massive extraorbital recurrent unilateral retinoblastoma that was operated previously at 4 months of age. As a cons...
Pulsed Intravenous Cyclophosphamide for Severe Ocular Inflammatory Disease: An International Experience
Study background: The purpose of this study is to assess the clinical response of intravenous pulses of cyclophosphamide for severe ocular inflammation. Methods: This is an observational and retrospective clinical study...
The Existence of mRNAs and miRNAs Expressions for Maintaining Cell Survival Networks Associated with the Human Transparent and Cataractous Lens
Background: Human lens cells have a long lifespan and so must maintain cell survival networks with regulate biological processes including gene expression and regulation. The purpose of this study was to identify mRNA tr...
A Mouse Model of Multi-DrugResistant Staphylococcus aureus-induced Ocular Disease
Staphylococcus aureus infection of the cornea is a significant threat to vision. The percentage of bacterial isolates resistant to antibiotics is increasing as is the percentage of infections caused by methicillin resist...