Oxidative Stress and Arsenic Exposure among Copper Smelters
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2014, Vol 4, Issue 15
Abstract
Copper is widely used in industry. It has been associated with several health hazards among exposed workers. Aim: to measure the indicators of oxidative stress as malondialdehyde level and superoxide dismutase enzyme activity and their association with copper and arsenic levels among copper smel=ter workers. Subjective and methods: This study was conducted on forty workers in a secondary copper smelting factory, who were occupationally exposed to copper. They were compared with forty non-exposed individuals. Full history, clinical examinations were done. Serum copper, serum arsenic, urinary arsenic, malondialdehyde and superoxide dismutase were measured. Environmental measurements of copper and arsenic dusts were carried out at different workplace areas. Results: Environmental measurements in the workplace were within the normal permissible limits in Egypt. Statistically significant differences were found between exposed and control as regards the prevalence of the respiratory and neurological symptoms. Compared to the control group, serum copper, serum arsenic, urinary arsenic and malondialdehyde blood levels were significantly higher among the exposed worker (P<0.01). Each one was positively correlated with the duration of employment. Superoxide dismutase activities in blood were significantly decreased and negatively correlated with the duration of employment. Conclusion: The disruption of hemostasis induced by oxidative stress may promote the development of health hazards with continued occupational exposure to copper fumes. Recommendation: Blood levels of malondialdehyde and superoxide dismutase enzyme activity can be used as indicators of oxidative stress among exposed workers.
Authors and Affiliations
A. El Safty, L. Rashed, A. Samir, H. Teleb
Keywords
Related Articles
- EP ID EP349428
- DOI 10.9734/BJMMR/2014/8284
- Views 82
- Downloads 0
Predictors of Positive Outcomes in Pulmonary Rehabilitation
Aims: The study aims were to (1) determine the effect of participation in pulmonary rehabilitation on quality of life, severity of dyspnea, and exercise tolerance (2) evaluate predictors (number of pulmonary rehabilitat...
Health Maintenance Organization-Federally Qualified Health Center (HMO-FQHC) Collaboration to Provide After-Hours Pediatric Primary Care: A Feasibility Study
Aims: Examine feasibility, implementation and impact of a Health Maintenance Organization (HMO)-Federally Qualified Health Center (FQHC) collaboration in providing after-hours care as an Emergency Department (ED) diversi...
Plantar Pressure Asymmetry in Patients Six Months after Surgical Treatment of Calcaneal Fractures in Adults
Aim: To compare plantar pressure distribution and contact time in patients in month 6 following operative treatment of calcaneal fractures. Study Design: Walking on the tensometric platform. Place and Duration of Study...
Differential Impact of Parental BMI and Diet on Overweight and Obesity in Young School Children in Southern Brazil
Aims: To analyze simultaneous impact of biological, socioeconomic and behavioral determinants of excess weight in schoolchildren. Study Design: Cross-sectional study based on a representative sample of schoolchildren fr...
Anopheles Species Prevalence, Diversity, Behaviour and Their Implications to Tourist Activities in Uyo, South-South Nigeria
Aims: Malaria poses a medical and public health challenge in Nigeria. The burden of the disease has been a major source of concern to tourists in Uyo. Knowledge on the biting behaviour and the Human Biting Rates (HBR) ar...