Oxidative stress and total antioxidant status in term newborns and their mothers
Journal Title: Annals of Agricultural and Environmental Medicine - Year 2015, Vol 22, Issue 4
Abstract
The peripartum period and delivery are considered critical for maintaining a balance between the production of free oxygen radicals and functional incompetence of the antioxidant system of a foetus and a neonate. [b]Objective.[/b] The aim of the study was to evaluate the oxidoreductive state of mothers and their newborns immediately after delivery and in the first few days after birth. [b]Method.[/b] Eighty-five mothers and their healthy, term newborns were included into the prospective study. Total antioxidant capacity (TAC) and thiobarbituric acid reactive substances (TBARS) in maternal placenta and milk, as well as blood and urine of the neonates on the first and third day after birth, were examined. [b]Results.[/b] Elevated levels of TBARS were found in maternal placenta and neonatal blood on the third day after birth, but low concentrations were observed in maternal milk. On the contrary, total antioxidant status (TAS) showed a declining tendency in neonatal blood and an increasing tendency in breast milk. Markers of oxidative stress and antioxidant capacity were independent of the mode of delivery. [b]Conclusions.[/b] Values of oxidative stress markers in mothers and newborns immediately after birth were elevated and increased further during the first few days of neonatal life. Breast milk was the only nutritional substance with high antioxidant activity. At the same time, TBARS levels in breast milk decreased, which might indicate its protective role in reducing oxidative stress in newborns.
Authors and Affiliations
Maria Wilinska, Tomasz Niemiec, Grzegorz Jakiel
Keywords
Related Articles
- EP ID EP81046
- DOI -
- Views 137
- Downloads 0
The PONS study and its place in the strategy of health gain in Poland
After 30 years (1960-1990) of adult health decline, since the beginning of the political and economic transformation in the early 1990s.a dramatic reversal of health trends is being observed in Poland, In contrast, in th...
Bioimpedance vector pattern in women with breast cancer detected by bioelectric impedance vector analysis. Preliminary observations
Introduction and objectives: The study was conducted to evaluate soft tissue hydration and mass through pattern analysis of vector plots as height, normalized resistance, and reactance measurements by bioelectric impedan...
Metabolic syndrome in Poland – the PONS Study
Introduction: In Central and Eastern European countries, cardiovascular disorders (CVD) in middle age are much more common than in Western Europe, and it is imperative to understand the causes underlying this excess dise...
Various aspects of physical activity among Lithuanian adolescents
Studies of the physical activity of 17-year-old adolescents attending selected schools in Lithuania were conducted in 2010 with the use of the IPAQ. The adolescents differed with respect to the scope of leisure time poss...
Characterization of Polish feline B. henselae isolates by multiple-locus tandem repeat analysis and pulse-field gel electrophoresis
Knowledge about molecular epidemiology of [i]B. henselae[/i] is important for recognizing the geographical distribution of strains and identification of isolates virulent for humans. Eleven Polish feline [i]B. henselae[/...