Oxytocin for labour induction or augmentation as a risk factor for autism: systematic literature review
Journal Title: Obzornik zdravstvene nege - Year 2017, Vol 51, Issue 2
Abstract
Introduction: Some studies have shown a potential association between oxytocin use during labour and autism spectrum disorder in children (ASD). We performed a systematic review of recent studies examining this association. Methods: Boolean operators (AND/OR) were used to search MEDLINE using the following search criteria: Autistic Disorder or Autism Spectrum Disorder or Autism and Labour Induction or Labour Augmentation. Articles published in English in 2013 or later were considered. Additional studies were identified by reviewing citations. Only studies conducted on people were included. Studies not accounting for potential confounding factors were excluded. Results: Four retrospective cohort studies met the inclusion criteria. One showed an association between labour induction and augmentation and ASD, one showed a weak association between labour augmentation in boys and ASD, and one showed no association between labour induction or augmentation and ASD. The largest study showed a weak association between labour induction and ASD, which was not significant when siblings were analyzed separately. Discussion and conclusions: Recently published studies do not support the hypothesis of a causal relationship between oxytocin use during labour and ASD. Benefits of medically indicated induction or augmentation of labour outweigh the theoretical risk of ASD.
Authors and Affiliations
Marija Grosek, Miha Lučovnik
Keywords
Related Articles
- EP ID EP301255
- DOI 10.14528/snr.2017.51.2.154
- Views 112
- Downloads 0
Vpliv terapije z lutko na življenje oseb, obolelih za demenco
Uvod: Terapija z lutkami sodi med nefarmakološke pristope v obravnavi oseb, obolelih za demenco, ki ugodno vplivajo na zmanjšanje duhovne in čustvene stiske, vznemirjenosti in izboljšajo komunikacijo. Namen sis...
Stress among employees in psychiatric nursing
Introduction: Evidence suggests that stressful situations are frequent in the field of psychiatry and that professionals working in this speciality are more prone to stress. Stressful situations may be compounded by igno...
Satisfaction of the citizens of the Republic of Slovenia with healthcare services
Introduction: Measurement of patient satisfaction with health services is an important development indicator of any healthcare system. Patient satisfaction is a significant and widely used indicator for measuring th...
The family medicine reference clinic: an example of interprofessional collaboration within a healthcare team
Since being introduced in 2011, family medicine reference clinics (FMRCs) have created several advantages in the treatment of patients, but have also drawn attention to areas where improvements could be made (Poplas Susi...
Prevalence and characteristics of tobacco and cannabis co-use in 15-year-old students in Slovenia
Introduction: While the co-use of tobacco and cannabis is common among adolescents, no data on this topic is currently available for Slovenia. The purpose of this study was therefore to explore the prevalence and&nb...