OXYTOCIN INDUCED NEONATAL HYPERBILIRUBINEMIA
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 21
Abstract
INTRODUCTION: Hyperbilirubinemia is one of the most common causes of health problems, observed in 60% of term and 80% of preterm infants in the first week of life. Hyperbilirubinemia leads to neurotoxicity in severe condition. Some studies suggests that liberal use of oxytocin for inducing labour is one of the factor which lead to neonatal hyperbilirubinemia. OBJECTIVE: To compare the effect of oxytocin and neonatal bilirubin levels with spontaneous vaginal delivery. MATERIALS AND METHODS: 100 full term parturients were selected for this study. The subjects were divided into two groups. 50 healthy babies of women who had oxytocin induced labour and 50 healthy babies of women with normal vaginal delivery following spontaneous onset of labour formed the control group. Neonatal serum bilirubin was measured on day 1, 3 and 5 after delivery. Bilirubin was measured by spectrophotometry. Data was analysed in ms excel sheet using spss 19.0v. Statistical analysis was done by using unpaired‘t’ test. RESULTS: There was significant increase in bilirubin level in oxytocin induced group compared to control group on day 1 and 3. There was insignificant increase in bilirubin level in oxytocin induced group on day 5. However the level of serum bilirubin is within normal limits as bilirubin level normally rises on till 4th day and decreases thereafter. CONCLUSION: Neonatal hyperbilirubinemia may be due to oxytocin administration by continues IV infusion which results in erythrocyte swell and rupture. Increase in bilirubin level in oxytocin induced group is within physiological limits.
Authors and Affiliations
Smita S. Patil, Manjunatha S, Veena H. C, Vinod Wali
Keywords
Related Articles
- EP ID EP228878
- DOI 10.18410/jebmh/2015/451
- Views 65
- Downloads 0
ANDROGEN RECEPTOR POSITIVITY AND PROGNOSIS OF UROTHELIAL CARCINOMA
BACKGROUND Urothelial carcinoma is a common condition and comprises 7% of all cancers and 3% of all cancer deaths. Globally, the incidence of bladder cancer has been increasing. Smoking is associated with increase in uro...
EARLY REMOVAL OF POST-OPERATIVE ABDOMINAL DRAIN AFTER RENAL TRANSPLANT IN PATIENTS WITH SIGNIFICANT LYMPHORRHOEA: RESULTS OF A SINGLE CENTRE OBSERVATIONAL STUDY
BACKGROUND Delay in post-operative abdominal drain removal due to excessive lymphorrhoea can lead to prolonged hospital stay and increase in risk of infections in patients with kidney transplant. This study was designed...
PREVALENCE OF OVERWEIGHT AND OBESITY AMONG ADOLESCENT SCHOOL CHILDREN IN AN URBAN AREA IN CENTRAL KERALA- A CROSS-SECTIONAL STUDY
BACKGROUND Childhood obesity is emerging as a serious public health problem among low and middle-income countries. Overweight and obese children are likely to stay obese into adulthood. They are more likely to develop no...
COMPARATIVE STUDY OF ENDOMETRIAL SAMPLING USING PIPELLE WITH HYSTEROSCOPIC-GUIDED BIOPSY
BACKGROUND Hysteroscopic-guided biopsy is the gold standard for endometrial sampling, but it carries risk of general anaesthesia, infection and perforation, whereas Pipelle does not require anaesthesia or cervical dilata...
OUR TEN YEARS’ EXPERIENCE WITH PULSE THERAPY IN PEMPHIGUS- A RETROSPECTIVE ANALYSIS OF 194 CASES
BACKGROUND Pemphigus is a group of autoimmune disease that affect skin and mucous membranes clinically manifested by flaccid blisters because of acantholysis. Pulse therapy was initiated in 1981 to treat the cases of pem...