Paediatric Malignant Soft Tissue Sarcoms: A Clinicopathological Study
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 1
Abstract
Pediatric soft tissue sarcomas (STSs) are a heterogenous group of malignant tumors originating from primitive mesenchymal tissue. They account for 7% of all childhood tumors. Risk-based management allows the pediatric oncologist to determine the risks and benefits of treatment for each patient in order to maximize survival, minimize morbidity, and improve the quality of life. Thus, accurate histopathological reporting in conjugation with ancillary methods is needed. We attempted to study the occurrence of soft tissue sarcomas in paediatric population. This study was under taken to evaluate the incidence and morphological features of malignant soft tissue sarcomas in children of fifteen years and below. The histopathology slides and paraffin blocks were reviewed. Gross examination was done carefully noting the size, shape, extent and configuration, nodularity, consistency (solid, cystic or mixed). The sections 3-5 μ thick, were cut and stained by haematoxylin and eosin in all cases and special stains like PAS, MTS, RT and IHC done where ever feasible. Thirteen cases were encountered, out of which 9(13.63%) were Rms, 3 (4.54%) were fibrosarcoma and 1 (1.51%) was synovial sarcoma. Case distribution included one in infancy, 2 in 1-5yr, 4 in 5-10yrs and 6 cases in 10-15 yrs age group. In the present study most common site was abdominal wall and the age group was between 10-15 yrs (46.15%). The mean age being 8 yrs 4mts. Sex ratio of M: F was 1.16:1.
Authors and Affiliations
Chandrashekhar Thotadamane Nagaraja, Geethalakshmi Ugrappa, Girish Chandrashekara Jarabandi, Rameshbabu K
Keywords
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