Paliperidone Palmitate-Induced Delirium in an Adolescent with Schizophrenia: Case report

Journal Title: Sultan Qaboos University Medical Journal - Year 2018, Vol 18, Issue 2

Abstract

Schizophrenia is a serious long-term mental disorder which usually presents in adolescence or early adulthood. However, poor adherence to oral antipsychotics can lead to relapse and rehospitalisation. We report an adolescent male with schizophrenia who was referred to the South London & Maudsley National Health Service Foundation Trust, London, UK, in 2015 due to worsening psychotic symptoms. Following poor compliance with oral medications, a four-week regimen of paliperidone palmitate long-acting injections was initiated, with an initial positive response. However, 10 days after the second dose, the patient developed severe acute-onset delirium with fluctuating levels of consciousness. Paliperidone palmitate was discontinued and the patient instead underwent a course of zuclopenthixol decanoate long-acting injections with a favourable outcome.

Authors and Affiliations

Hassan Mirza, Duncan Harding, Naser Al-Balushi

Keywords

Related Articles

Resuscitation & Research Conference 2018

Objectives: Tis study aimed to review scorpion sting (SS) management practices in Omani tertiary care emergency departments. Methods: Tis retrospective study included all emergency SS cases at three tertiary hospitals i...

Effect of Zinc Supplementation on Morbidity due to Acute Diarrhoea in Infants and Children in Sanaa, Yemen A randomized controlled double blind clinical trial

Objectives: To study the impact of zinc administration on the morbidity and mortality attributed to diarrhoea among children less than 5 years old. Methods: Te study design was a randomized double blinded controlled cli...

Diabetes Care in Oman Obstacles and solutions

Diabetes has become one of the most challenging chronic diseases with its prevalence increasing in most countries worldwide. Te Arabian Gulf countries face a similar increasing prevalence of diabetes. Diabetes care req...

Early versus Late Parenteral Nutrition in Very Low Birthweight Neonates A retrospective study from Oman

Te aim of this study was to compare the biochemical parameters, weight gain, osteopenia and phosphate supplementation in very low birth weight (VLBW) neonates receiving early versus late parenteral nutrition (EPN versu...

Cardiovocal Syndrome A rare cause of hoarseness in a patient with a history of pulmonary tuberculosis

Hoarseness is a common clinical condition with underlying causes which can vary from reversible and benign to life-threatening and malignant. Cardiovocal syndrome may cause hoarseness secondary to left recurrent laryng...

Download PDF file
  • EP ID EP34698
  • DOI http://dx.doi.org/10.18295/squmj.2018.18.02.014
  • Views 330
  • Downloads 0

How To Cite

Hassan Mirza, Duncan Harding, Naser Al-Balushi (2018). Paliperidone Palmitate-Induced Delirium in an Adolescent with Schizophrenia: Case report. Sultan Qaboos University Medical Journal, 18(2), -. https://europub.co.uk/articles/-A-34698