Papillary Neoplasms of Breast- Experience at a Cancer Centre in South India
Journal Title: Scholars Academic Journal of Biosciences - Year 2017, Vol 5, Issue 3
Abstract
Papillary neoplasms of breast are a rare entity which poses diagnostic challenge to pathologists. There is limited data regarding this entity in Indian population, majority being case reports. Our objective is to evaluate the demographic, clinicopathologic, survival characteristics and management protocols of this rare entity. This is a retrospective audit of cases reported as papillary neoplasms of breast over a period of 4 years (2013-2016). Data of these patients is retrieved from the Institutional Cancer Registry. A total of 20 cases of papillary neoplasms are diagnosed during this period of which there are16 cases of invasive carcinomas, three cases of carcinoma in situ and a single benign lesion. Mean age of presentation is 57 years, 70% being postmenopausal. There was a single case of male papillary carcinoma. FNAC was done in 55% of cases, with a definite diagnosis of carcinoma in 27% of cases. 60% of cases showed a cystic appearance grossly. Most common histologic type among carcinomas was encapsulated papillary carcinoma with invasion (36%). IHC was performed for myoepithelial markers in all cases and for hormonal status in carcinomas. ER positivity noted in74%, PR positivity in 68% and HER2 positivity in 10% cases. Most carcinomas are of clinical stage IIA and MRM was the most common surgical treatment. In case of carcinomas , mean follow up is 24 months with 94% cases showing disease free survival. There was no incidence of mortality till the last follow up.
Authors and Affiliations
Sithara Aravind, Sangeetha K Nayanar, Noushad Aryadan, Sajith K Satheesh, Sampada Desai, SatheeshBabu TV
Keywords
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