Paramountcy of platelet parameters in thrombocytopenia- Our hospital experience
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 4
Abstract
Introduction Thrombocytopenia defined as platelet count below 150000ul This fall in platelet count may be due to decreased production increased destruction and pooling of platelets The platelet parameters include platelet count mean platelet volume MPV platelet distribution width PDW obtained by automated cell counters These help in knowing the pathomechanism of myriad cases of TCPs Hence the present study was undertaken to know the variations and correlations of platelet parameters in various causes of TCPsMaterials and Methods 700 blood samples of patients with platelet count 150000 ul were studied Hematological analysis was done by Sysmex KX21 Platelet parameters of all the cases and control group were noted The cases were grouped into various categories of A B or C depending on mechanism of decrease in platelets Data was analyzed and tested for statistical significance using oneway ANOVA and post hoc testing using Tukeys testResults Majority of the cases in the present study were in group A 753 followed by group B 239 and group C 06 A higher value of MPV 1015130 fl and PDW 1444235 was found in group A compared to other categories Significant results of MPV and PDW values were seen in group A and group B categoryConclusion Platelet parameters like MPV and PDW obtained by automated cell counters together with platelet counts help us to know the pathomechanism of various causes of TCPs which inturn provides pivotal information for better management Keywords Thrombocytopenia Platelet count Mean platelet count Platelet distribution width
Authors and Affiliations
K Geetha Mala, Bhumika J Bhandari, Shreekant K Kittur
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