Parathyroid Carcinoma- A Case Report
Journal Title: GUJARAT CANCER SOCIETY RESEARCH JOURNAL - Year 2013, Vol 15, Issue 1
Abstract
Parathyroid carcinoma is a rare endocrine neoplasm. Although most patients present with hyperparathyroidism, it is difficult to distinguish preoperatively parathyroid carcinoma from its benign counterpart (parathyroid adenoma), due to their nonspecific clinical features, biochemical profile and imaging findings. Usually it is associated with more severe clinical manifestations and biochemical profile than parathyroid adenoma. Surgery with en bloc tumor resection is the only curative treatment. We report a case of 34 year old female who presented with pathological fracture of left femur with severe hypercalcemia and primary hyperparathyroidism. Imaging studies were not conclusive as to whether it was parathyroid adenoma or carcinoma. Right inferior parathyroidectomy was performed. Postoperative serum calcium and parathyroid hormone (PTH) returned to normal. Final histopathology examination revealed parathyroid carcinoma.
Authors and Affiliations
Purvi Patel, Krutarh Thakkar, Abhishek Pareek, Manish Kumar, Dinesh Yadav, Gopal Girdhar, Beena Brahmbhatt, Shashak Pandya, Mukul Trivedi
Keywords
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