Pathophysiology and Potential Clinical Significance of Il-5: A Review Article
Journal Title: International Journal of Health & Medical Research - Year 2025, Vol 4, Issue 01
Abstract
Interleukins belong to the group of cytokines that play a key role in immune system cell signaling. Among them, Interleukin-5 (IL-5) gains paramount significance in the regulation of eosinophils, which are thinly scattered in most allergic as well as inflammatory conditions, especially asthma. A biochemical characterization of IL-5 is a prerequisite for understanding the basic aspects of its function and finding a precise treatment. Interleukin-5 (IL-5) is a critical cytokine that primarily drives the development and differentiation of eosinophils and B cells, playing a key role in the allergic response and the pathogenesis of asthma. Therefore, the knowledge of its biochemical structure is a prerequisite for any plan to develop targeted therapies for eosinophilia-related diseases. The clinical relevance of interleukins resides in their regulatory capabilities of immune responses, with an ever-growing recognition in diverse pathologies such as allergic manifestations, autoimmune diseases, or neoplastic processes. Interleukins in clinical application should be the focus of research, specifically IL-5, synthesizing observable from the latest related studies and knowledge deficits that should entice future research in the same line. This paper, therefore, gives a review based on already existing research findings concerning the biochemical structure of IL-5.
Authors and Affiliations
Noor Jamal Mohammed, Ali A. Al-fahham,
The Crucial Roles of Geospatial Techniques in the COVID-19 Fight: A Systematic Review
The Corona Virus Disease 2019 (COVID-19) appeared in Wuhan, China, at the end of 2019, spreading from there across China and the whole world. Such advanced technologies as geospatial techniques have been applied to figh...
Giardiasis: Diagnosis, Pathogenesis and Treatment
Giardiasis has become a worldwide health problem and it is the most frequent cause of diarrhea in both pediatric and adults’ patients. Ingestion of cysts directly or indirectly via the fecal-oral route is the main mode o...
Symptomatic Primary Umbilical Endometriosis: A Case Report and A Review of the Literature
Endometriosis is a condition defined as extrauterine functional endometrial tissue, typically seen on pelvic peritoneal surfaces, leading to symptoms such as cyclic pain, dysmenorrhea, dyspareunia, and infertility. Extra...
Evaluation of Some Aspergillus Mycotoxins in Patients with Bronchitis in Al-Najaf City
This research aimed to establish whether the Aspergillus species identified from bronchitis patients were mycotoxigenic or non-mycotoxigenic fungi in sputum and serum samples. A total sample of 170 subjects with ages ran...
Hellp’s Syndrome – Maternal Morbimortality, Clinical Case Report
Introduction: HELLP syndrome is a hypertensive disorder of pregnancy associated with severe maternal-fetal complications and representing high morbidity and mortality. Objective: A clinical history of HELLP syndrome as...