Pathophysiology, Clinical consequences, Epidemiology and Treatment of Hyperurecemic gout
Journal Title: RADS Journal of Pharmacy and Pharmaceutical Sciences - Year 2018, Vol 6, Issue 1
Abstract
Hyperuricemia is a common metabolic disorder worldwide with an increased level of serum urate/ uric acid (UA) up to 6.8 mg/Dl. It is a precursor of gout, a rheumatic inflammatory disease characterized by the deposition of uric acid in the form of monosodium urate (MSU) crystals in joints. It may be due to under secretion or over production or both. MSU crystals stimulated a powerful inflammatory reaction resulted in acute pain in joints. There are various marketed drugs used for the treatment of hyperuricemia i.e. allopurinol and Febuxostat .globally the prevalence of hyperurecemic gout is increasing day by day, it is 138th ranked factor of disability.it is more prevalent in male as compared to female and more present in developed countries than underdeveloped countries .it can be minimize by life style modification. Present attempt has been made to summarize the pathophysiology, clinical consequence, epidemiology and conventional treatment of hyperurecemic gout.
Authors and Affiliations
Shifa Shaffique
Keywords
Related Articles
- EP ID EP604396
- DOI -
- Views 167
- Downloads 0
Collagen and Collagenases: A Brief Review
Collagen is the most important and abundant protein in the human body that is needed for a number of physiological functions such as tissue repair during wound and fracture healing. There are about thirty different types...
Hypertension and Related Risk Factors Among Clients on Combined Antiretroviral Therapy in Offa, Nigeria
Justification: The hypertension pervasiveness is a major challenge in human immunodeficiency virus (HIV) afflicted people globally. Aim: A prospective, cross-sectional research comprising two hundred and eighteen HIV af...
Quantitative HPLC Analysis of Vitamin D3 and Gallic Acid in Vivabon syrupfor Children Growth
Objective:The current study was conducted to evaluate quantitative estimation of the biomarkers gallic acid and Vitamin D3 present in Vivabon-D3 syrup Backgrounds:Vivabon-Vitamin D3 is a poly herbal syrup formulation fo...
Comparative Analysis of Antibacterial Activity of Ciprofloxacin and Homeopathic Mother Tincture
Objective: The aim of this study was to evaluate and compare in vitro antibacterial effects of ciprofloxacin and homeopathic mother tinctures. Methods: All the experimental homeopathic mother tinctures were donated by M...
Traditionally Used Plants with the Inhibitory Effect of Platelet Aggregation
During hemostasis, after vascular injury and wound healing process, platelets play a very significant role, where the platelets hypersensitivity is also related to the progression or development of various cardiovascular...