Pattern of dyslipidemia in ischemic stroke
Journal Title: Journal of Medical and Allied Sciences - Year 2015, Vol 5, Issue 2
Abstract
The study aimed to assess dyslipidemia pattern including role of non HDL cholesterol (non HDLc) in ischemic strokes. A retrospective descriptive was conducted on 80 patients who were admitted to Osmania General Hospital between May 2013 and May 2015 with new onset of stroke. A detailed history, physical examination and outcome details were collected from the hospital medical records. Data such as fasting lipid profile was noted, non HDLc was calculated, computed tomography (CT) or magnetic resonance imaging (MRI) brain reports were collected from medical records. Among enrolled patients, 55 were males and 25 were females. Age distribution: <40 years, n=4; 40-60 years, n=50; and >60 years, n=26. Dyslipidemia as per ATP III guidelines was present in 92.5% cases (n = 74). In our study, high LDL was found in 16 cases (21.62%), high total cholesterol in 16 cases (21.6%), low HDL in 57 cases (77%), high triglycerides in 13 cases (17.56%) and elevated non HDLc (>130mg/dl) in 28 patients (37.8%). Risk factors for stroke present were hypertension (n=48, 60%), diabetes (n=18, 22.5%), both diabetes and hypertension (n=15, 18.75%), smoking (n=33, 41.25%), alcoholism (n=32, 40%) and more than 2 risk factors were present in 28.75% (n=23). Total number of deaths was 05%. To conclude, most of the patients were having low HDL (<40mg/dL) which is an independent risk factor for stroke. This study also highlights the importance of elevated non HDL Cholesterol in development of ischemic stroke, which is more comprehensive measure of atherogenic lipoprotein than LDL cholesterol alone. This study upholds the importance of life style modifications to cut down the risk of development of stroke and also to evaluate the association between elevated nonHDL cholesterol in stroke patients.
Authors and Affiliations
Siddeswari R| Department of General Medicine, Osmania General Hospital, Afzal Gunj, Hyderabad-500012, Telangana, India, Manohar S| Department of General Medicine, Osmania General Hospital, Afzal Gunj, Hyderabad-500012, Telangana, India, Sudarsi B| Department of General Medicine, Osmania General Hospital, Afzal Gunj, Hyderabad-500012, Telangana, India, Suryanarayana B| Department of General Medicine, Osmania General Hospital, Afzal Gunj, Hyderabad-500012, Telangana, India, Shravan Kumar P| Department of General Medicine, Osmania General Hospital, Afzal Gunj, Hyderabad-500012, Telangana, India, Abhilash T| Department of General Medicine, Osmania General Hospital, Afzal Gunj, Hyderabad-500012, Telangana, India
Keywords
Related Articles
- EP ID EP12726
- DOI -
- Views 382
- Downloads 50
Perceived stress in Saudi undergraduate medical students
This study aimed to assess the prevalence and magnitude of stress in Saudi undergraduate medical students and its associated sociodemographic factors using a cross-sectional design. It was conducted at King Khalid Univ...
Lobular capillary hemangioma of esophagus mimicking Barrett’s esophagus
A 30 year old male patient presented to the outpatient department of Gastroenterology with complaints of dyspepsia of 6 months duration associated with progressive dysphagia to solids and liquids. There was no noticeab...
Homology modeling and ligand interaction of human trafficking protein particle complex subunit 3-like protein and its correlation with Alzheimer’s disease
In order to understand the mechanism of molecular interactions at active sites of trafficking protein particle complex (TRAPPC) subunit 3-like protein (Accession number Q5T215) homology modeling and docking studies we...
Antibiotic resistance: Clear and present danger
Determinants of contraceptive use among married women residing in rural areas of Belgaum
Today the world population is around 7 billion and India harbours 1.2 billion. One of the reasons for uncontrolled growth of the population is unregulated fertility. Unregulated fertility many a times leads to unintend...