Patterns of antimicrobial resistance among Multi-Drug resistant Escherichia coli in a tertiary care centre in South Karnataka
Journal Title: Indian Journal of Microbiology Research - Year 2017, Vol 4, Issue 1
Abstract
Introduction: Emergence of multi-drug resistant (MDR) organisms is an important public health concern especially in developing countries. The present study was carried out to assess the current antimicrobial pattern of multi-drug resistant Escherichia coli. Materials and Methods: 346 consecutive, non-duplicate isolates of E. coli isolated during a period of two years were included in the study. The numbers of multi-drug resistant isolates were determined. Their antimicrobial resistance phenotypes and Multiple Antibiotic Resistance (MAR) index were determined. Results: Among the 346 isolates of E. coli, 297 (85.84%) were multi-drug resistant with 61.3% of the isolates being resistant to drugs in more than five antimicrobial categories. The Multiple Antibiotic Resistance index of 82.7% of isolates was found to be greater than 0.2. Carbapenems, aminoglycosides, Chloramphenicol and Nitrofurantoin were found to be the most effective agents against MDR E.coli. Conclusion: Antimicrobial resistance profiles of bacteria are ever-changing and periodic evaluation of resistance phenotypes of isolates is essential for the formulation of appropriate antibiotic policy and initiation of pertinent empirical therapy.
Authors and Affiliations
Soumya Kaup, Sunitha B. U. , Jaya Sankarankutty
Keywords
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- EP ID EP293880
- DOI 10.18231/2394-5478 .2017.0011
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