Patterns of failure in patients with lung carcinoma after treatment by different modalities
Journal Title: Medpulse International Journal of Medicine - Year 2019, Vol 9, Issue 2
Abstract
Background: Lung cancer is a major health problem worldwide. Patterns of failure can be local (lung parenchyma, bronchial stump, chest wall), regional (mediastinal lymph nodes) or distant (brain, liver and bone). Aim: To study the patterns of failure in patients with lung carcinoma after treatment by different modalities. Material and Methods: Patients with histologically confirmed Carcinoma Lung, registered between January 2008 to December 2012 and treated by Radiotherapy/Chemotherapy/Surgery or any combined modality were included. Follow up details were thoroughly studied with regard to loco-regional failure, distant failure, overall survival. Results: Only 558 (out of 714) patients were available for evaluation after completion of treatment. 34 patients (6.09%) had complete response, 128 patients (22.94%) had partial response and 122 patients (21.86%) had stable disease. 274 patients (49.10%) had progression of disease. 19 patients have recurrence of the disease out of 34 patients who had complete response. 27 patients with squamous cell cancer who had complete response, 16 recurred and out of 6 patients with adenocarcinoma who had complete response, 3 had recurrence. 3 patients had local, 2 had regional, 2 had loco-regional, 6 had distant and 6 had local+ regional +distant failure. Conclusion: Educating people about lung cancer, smoking cessation, early diagnosis, early treatment, nutritional support, combined modality of treatment and proper follow-up can help these patients reduce failures and improve survival.
Authors and Affiliations
Goldee Khurana, Pawan Kumar, Nazir Khan
Keywords
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- EP ID EP516396
- DOI 10.26611/10219212
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