Pediatric Exposures to Persistent Environmental Chemicals
Journal Title: Pediatrics and Neonatal Nursing – Open Journal - Year 2014, Vol 1, Issue 1
Abstract
Traditional risk factors are responsible for about 70% of the population attributable risk of Cardiovascular Disease (CVD).1 Common environmental exposures are known to be responsible for some portion of the remaining 30%. Therefore, it is important to study chemicals like the class known as Perfluoroalkyl Chemicals (PFCs) or Perfluoroalkyl Substances (PSASs). Two of the most highly studied PFCs are Perfluorooctanoic Acid (PFOA or C8) and Perfluorooctane Sulfonate (PFOS or C8S). PFCs are persistent in the environment and associations have been shown with a whole host of negative health outcomes in laboratory animals, including endocrine-disrupting properties as well as developmental effects.2 To make matters worse, PFCs have been detected in the blood of >98% of the US population3 and epidemiological studies have demonstrated associations between PFOA and PFOS, and many negative health outcomes such as cancer,4 CVD,5 steoarthritis,6 hyperuricemia,7 pregnancy-induced hypertension,8 endocrine disruption,9 dyslipidemia,10,11 and reproductive effects,12,13 often times even at baseline levels typical of the general population’s exposure level.
Authors and Affiliations
Sarah Dee Geiger
Keywords
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- EP ID EP555770
- DOI 10.17140/PNNOJ-1-e001
- Views 126
- Downloads 0
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