Pediatric Mixed Functioning Adrenocortical Carcinoma: A Case Report and Review of Literature
Journal Title: Middle East Journal of Cancer - Year 2019, Vol 10, Issue 4
Abstract
Adrenocortical carcinoma (ACC) is a very rare disease in the pediatric age group. The clinic-biological profile, histopathological criteria of diagnosis, and staging of this disease in this age group are different from those of adult ACC. In this paper, we report a case of pediatric ACC presenting as Cushing syndrome that was managed with complete surgical excision. Through this case presentation, we highlight the sequential protocol of investigations and management in a child suspected of having ACC.
Wilms’ Tumor: Histopathological Variants and the Outcomes of 31 Cases at a Tertiary Care Center in Northern India
Background: Wilms’ tumor is the most common malignant renal tumor in the pediatric age group. This tumor is classically managed by multimodal treatment which involves surgery, radiotherapy and chemotherapy. While there i...
Analysis of EVI1 Gene Expression in Acute Myeloid Leukemia Patients in the Northeast of Iran
Background: Acute myeloid leukemia (AML) is a heterogeneous disease characterized by increasing immature blood cells in the bone marrow. Aberrant expression of specific genes is a common finding in AML. The proto-oncogen...
Interplay between CKS2, N-cadherin, and PD-ECGF in Non-Schistosomal and Schistosomal-Associated Bladder Cancer: A Prospective Comparative Study in the Egyptian Population
Background: The current study investigated the possible role of the cell cycle regulator, cyclin-dependent kinases regulatory subunit-2; the angiogenic factor, plateletderived endothelial cell growth factor; and the cell...
The Association of Vitamin D Deficiency with Colorectal Cancer: A Wake-up Call for Physicians and Health Authorities
Although there is evidence that vitamin D deficiency leads to the development of several cancers, including colorectal cancer, research has shown gaps in establishing a relationship between hypovitaminosis D and the inci...
PTEN and p53 Gene Expressions in Breast Cancer Specimens and their Clinicopathological Significance
Background: Breast cancer is the second leading cause of cancer death after lung cancer. Discovering molecular biomarkers is necessary for disease management that includes prognosis prediction and preventive treatment. T...