Pelvic Exenteration for Recurrent Rectal Cancer: A Single Institution Experience
Journal Title: Turkish Journal of Colorectal Disease - Year 2021, Vol 31, Issue 1
Abstract
Aim: Rectal cancer is an important cause of cancer-related deaths worldwide (1-2). Although rectal cancers can be diagnosed earlier nowadays due to the development of screening programmes, 18% of patients have a locally advanced stage at the time of diagnosis (3). Despite the improvements in total mesorectal excision and oncological treatments, the locoregional recurrence rates vary between 6-10% in rectal cancer patients (4-5). Method: The data of patients who underwent pelvic exenteration for recurrent rectal cancer in our clinic between January 2015 and December 2019 were retrospectively analysed. Results: It was found that the patients with lymphovascular invasion (LVI) and perineural invasion (PNI) showed statistically poor survival rates (p=0.038/0.022). Two of the patients had a positive surgical margin and two others had a positive radial margin. There was no statistically significant difference between surgical margin positivity and prognosis (p>0.05). The mean number of metastatic lymph nodes was 4.0 (0-12), and the total number of lymph nodes was 12.35 (2-27). There was no statistically significant difference between patients with lymph node metastasis in terms of survival (p=0.079). Seven of the patients (41.1%) received systemic treatment before the surgery. It was statistically determined that the patients who received this treatment showed better survival rates (p=0.045). Conclusion: It was found that pelvic exenteration had a positive effect on survival and local recurrence in recurrent rectal cancer, and that neoadjuvant therapy increased survival rates.
Authors and Affiliations
Serdar Culcu, Cemil Yüksel, Mahmut Onur Kültüroğlu, Fatih Göksel, Eda Güner, Bülent Aksel,Lütfi Doğan
Keywords
Related Articles
- EP ID EP693140
- DOI 10.4274/tjcd.galenos.2020.2020-8-1
- Views 103
- Downloads 0
Effects of Calcium Dobesilate on Colonic Anastomosis Healing: An Experimental Study
Aim: Anastomotic leakage in colon anastomosis (CA) increases morbidity and mortality. Calcium dobesilate (CaD) has angioprotective, antioxidant, lymphatic flow enhancing-and neuroprotective effects. Despite these capilla...
Penetrating Sharp Object Injury in the Gluteal Region and Small Bowel Perforation Due to Pelvic Penetration: A Case Report
Penetrating sharp object injuries in the gluteal region are common. However, it is very rare that these injuries lead to perforation of the small bowel by pelvic penetration, which is generally overlooked. As penetration...
Acute Hemorrhagic Incarceration of Prolapsed Giant Rectal Tubulovillous Adenoma: A Rare Case of Anorectal Emergency
Colorectal adenomas are polyps that arise from the mucosa and demonstrate neoplastic features. Increasing dysplasia and malignant potential of adenomas are related to their size, villous component, and patient’s age. Gia...
Laparoscopic Resection of Primary Tumor with Synchronous Conventional Resection of Liver Metastases in Patients with Stage 4 Colorectal Cancer: A Retrospective Analysis
Aim: Aim of this study is to analyze the short and long term results of laparoscopic colorectal cancer resection with synchronous conventional resection of liver metastasis. Method: All cases operated on synchronous col...
Robotic Low Anterior Resection and TAH+BSO with Transvaginal NOSE
In the last century, laparoscopic interventions have been developed to minimize the somatic and phsiological effects of surgery. Laparoscopic approaches have become frequently used in colorectal surgery as well. In recen...