PENETRATION ENHANCEMENT OF MEDICINAL AGENTS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 5
Abstract
Many current therapeutic agents like antibiotics, ionizable and peptide drugs are impermeable or do not possess the requisite physicochemical properties for efficient transport through outer tissue barrier to attain therapeutic blood level. For this reason the delivery of such drugs through barriers is currently one of the major interests in pharmaceutical research. Penetration enhancers or promoters are agents that have no therapeutic properties of their own but can transport the sorption of drugs from drug delivery system onto the skin and / or their subsequent transdermal permeation through skin. Numerous harmless and non-toxic penetration-enhancing compounds were found from both natural substances and synthetic products. Penetration enhancers are used to maintain the drug level in blood and to improve the efficacy of drugs.
Authors and Affiliations
Ganesh Sharma , Jyotsana Sanadya , Avinash Kaushik , Abha Dwivedi
Keywords
Related Articles
- EP ID EP119681
- DOI -
- Views 105
- Downloads 0
STUDY OF THE ANTIHYPERLIPIDEMIC, ANTIOXIDATIVE AND ANTIATHEROGENIC ACTIVITY OF TRITICUM AESTIVUM LINN. IN RABBIT RECEIVING HIGH FAT DIET
The aim was to study of the antihyperlipidemic, antioxidative and antiatherogenic activity of Triticum aestivum Linn. in rabbit receiving high fat diet. Twenty rabbits of either sex were taken and divided into four group...
NEUROBIOLOGICAL MODULATORS OF ANXIETY
Anxiety can be a core symptom of various mental/ behavioral disorders such as major depressive disorders, obsessive-compulsive disorders, panic disorder, adaptive disorder, post-traumatic stress disorder, social withdraw...
ANTIOXIDANT ACTIVITY OF FLAVONOID FROM ANREDERA CORDIFOLIA (TEN) STEENIS LEAVES
A flavonoid 8-Glucopyranosyl-4’,5,7-trihydroxyflavone, have been isolated from the methanol extract of leaves of Anredera cordifolia (Basellaceae). The structures of these compounds were established based on spectrosco...
A REVIEW OF LEPIDAGATHIS CRISTATA
The medicinal plants are widely used by the traditional medicinal practitioners for treating various diseases in their day to day practice and in the traditional medicine different parts of the plant are used (leaves, fl...
EVALUATION OF PROTECTIVE ROLE OF QUERCETIN ON PACLITAXEL-INDUCED LIPID PEROXIDATION
The objective of the present study was to explain antiperoxidative potential of quercetin on paclitaxel-induced lipid peroxidation. Goat liver was used as lipid source. This in vitro work was carried out by measuring usi...