Performance Characteristics of Two Immunochromatography Kits in the diagnosis of Malaria in Port Harcourt, Southern Nigeria.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 10
Abstract
Malariais a major cause of morbidity and mortality in Nigeria and Africa as a whole and a menace to humanity in the tropical regions of the world, yetproperdiagnosisof thisdeadlydiseaseposes a great challenge to mostendemicnations of the world. In view of this, astudywasdone to determine the performance characteristics of two commercially available Rapid Diagnostic Test (RDT) kits; CTK Onsite and SD Bioline relative to Giemsa-stained blood film microscopy within Port Harcourt, Southern Nigeria. A total of 400(226 males and 174 females) subjects between the ages of 11 and 60years were recruited for this study at the Out Patients Department (OPD) of the University of Port Harcourt Teaching Hospital(UPTH). The studyshowed a sensitivity,specificity, Positive Predictive Value, Negative Predictive Value and Accuracy of 78.7%, 100%, 100%, 73% and 86.5% respectively for CTK Onsite comparedto 36.2%, 100%, 100%, 47.4% and 59.5% recorded for SD Bioline. Hence this study showed that CTK Onsite is a better choice kit than SD Bioline for effective diagnosis of falciparum malariabut microscopy remain the gold standard as it detected more malaria cases than both kits.
Authors and Affiliations
Dada A. E, Eze C. N
Keywords
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- EP ID EP401639
- DOI 10.9790/0853-1710045155.
- Views 45
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