Period Prevalence of Bronchiectasis in Moderate and Severe COPD
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 5
Abstract
Chronic obstructive pulmonary disease (COPD), a common preventable and treatable disease characterised by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Exacerbations and comorbidities contribute to overall severity in individual patients. Many studies have observed an association between the COPD and bronchiectasis, reporting the presence of bronchiectasis in up to 50% of patients with moderate to severe COPD, this suggests that there may be a causal relationship in which COPD is a risk factor for bronchiectasis. Aim of the study: To find the prevalence of bronchiectasis in association with severe and moderate COPD admitted in Respiratory medicine department, Trivandrum over a period of 2 years Secondary Objective: Relating dyspnoea scale (MMRC), FEV1, amount of daily sputum production (<10 ml,10 ml-30ml,>30 ml) to bronchiectasis. Study design: Hospital based cross sectional study. Study Period: January 2012-November 2013. Study Population: Patients admitted to Respiratory medicine department between the study period who are diagnosed as COPD and labelled as severe and moderate COPD according to GOLD guidelines. Moderate FEV1 50% ≤ FEV1 < 80% predicted. Severe FEV1 <50% Predicted. Exclusion criteria: Other causes such as patients with old history of tuberculosis. Patient not fit to undergo HRCT as suggested by radiologist. Patient not willing to participate. Methodology: Patient diagnosed as severe or moderate COPD who were willing to participate in the study underwent HRCT from our radiodiagnosis department. Also includes a questionnaire regarding exacerbations, smoking index, dyspnoea scale (MMRC), current smoking status, sputum culture if admitted for infective exacerbations. HRCT was read independently by a radiologist and chest physician with control blinding. If both agree then it will be taken into account. We also try to prove an association between various factors studied through questionnaire and bronchiectasis. Results & Conclusion: The period prevalence of bronchiectasis in patients with moderate and severe COPD was 34.7%.MMRC (grading), FEV1, years of COPD had significant correlation with presence of bronchiectasis in moderate and severe COPD. Right lower lobe was the most common site. Cylindrical bronchiectasis was the most common type
Authors and Affiliations
Dr Jaya prakash. B
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