Periodontal Condition in Patients with Rheumatoid Arthritis: Effect of Anti-rheumatic Drugs
Journal Title: Journal of Dentistry, Shiraz University of Medical Sciences - Year 2019, Vol 20, Issue 3
Abstract
Statement of the Problem: Rheumatoid arthritis and periodontitis are chronic inflammatory diseases with a possible bidirectional relationship. This link may be affected by many factors like drug consumption. Purpose: This study was designed to evaluate the periodontal condition in patients with rheumatoid arthritis, considering the effect of disease modifying anti-rheumatic drugs. Materials and Method: This case-control study included 25 newly diagnosed rheumatoid arthritis patients with negative history of taking anti-rheumatic drugs, 25 patients who received anti-rheumatic drugs for more than three years and 50 healthy individuals as a control group. Periodontal indices, including plaque index, gingival index, probing depth, clinical attachment loss, and rheumatologic indices were recorded and compared between these groups. Results: Rheumatoid arthritis patients were significantly more affected by periodontitis compared with healthy subjects (p= 0.006). There was no significant difference in rheumatologic indices between patients with and without periodontitis. Clinical attachment loss in old rheumatoid arthritis patients and gingival index in newly diagnosed ones were significantly more compared to the control group (p= 0.003 and p< 0.001 respectively). We could not find a linear relationship between the severity of rheumatoid arthritis and chronic periodontitis (p= 0.1, r= -0.224). Conclusion: Periodontitis and clinical attachment loss were more in patients with rheumatoid arthritis than the healthy group, especially in drug consumers. Gingival index in patients without the history of consuming anti-rheumatic drugs was significantly higher than those who were drug consumers, indicating the effect of the medications on the signs of inflammation.
Authors and Affiliations
Samira Kordtabar, Mehrdad Aghaie, Elham Fakhari, Mohammad Ali Vakili
Keywords
Related Articles
- EP ID EP636093
- DOI -
- Views 83
- Downloads 0
Photogrammetric Comparison of Facial Soft Tissue Profile before and after Protraction Facemask Therapy in Class III Children (6-11 Years Old)
Statement of the Problem: Achieving a normal soft tissue facial profile is considered to be the main concern of class III patients and the goal of most class III treatments. Purpose: The purpose of this study was to inve...
Effect of the of Zeolite Containing Silver-Zinc Nanoparticles on the Push out Bond Strength of Mineral Trioxide Aggregate in Simulated Furcation Perforation
Statement of the Problem: Recently, zeolite has been regarded to improve the properties of dental materials such as mineral trioxide aggregate (MTA). Purpose: The aim of the present study was to evaluate the effect of i...
Effect of 940nm Diode Laser Irradiation on Microtensile Bond Strength of an Etch and Rinse Adhesive (Single Bond 2) to Dentin
Statement of the Problem: Laser can influence bonding mechanism by increasing the penetration depth of adhesive in smear layer. The effect of 940 nm diode laser on microtensile bond strength of adhesive to dentin has not...
Postoperative Pain Management after Impacted Third Molar Surgery with Preoperative Oral Lamotrigine, a Randomized, Double-blind, Placebo-Controlled Trial
Statement of the Problem: Extraction of the impacted third molar is often associated with severe postoperative pains, management of which are a big challenge. Lamotrigine is a new antiepileptic drug with pre-emptive anal...
Prevalence of Human Papilloma Virus in Sinonasal Papilloma in Southern Iranian Population
Statement of the Problem: Sinonasal papilloma (SNP) is a rare benign lesion characterized by high recurrence rate and malignant transformation. Purpose: This study aimed to investigate the prevalence of human papilloma...