Peripheral neuropathy as a rare syndrome related to metronidazole usage: Metronidazole may lead to persistent neuropathy

Journal Title: Medical Science and Discovery - Year 2016, Vol 3, Issue 5

Abstract

Metronidazole is a potent drug used against some protozoa like Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis and Balantidium coli, and anaerobic bacteria. It is used for the treatment of alcoholism, Crohn’s disease, exophthalmos, rheumatoid arthritis, rosea and acne as well. It is a well-tolerated drug with some kinds of side effects like abdominal pain, headache, nausea and metallic taste. Rarely but severely, pseudomembranous colitis, epileptic seizure, encephalopathy and peripheral neuropathy might be seen. These side effects are generally self-limited. Drug administration should be stopped immediately in case of these side effects’ existence. In this article, we presented a case which used metronidazole for hepatic ameobiasis in a time period of 4 and a half months, and developed peripheral neuropathy.

Authors and Affiliations

Mehmet Aydin, Refah Sayin

Keywords

Related Articles

Effects of sevoflurane and desflurane on the blood and plasma viscosity

The purpose of present study was to compare the effects of desflurane and sevoflurane on blood viscosity in three different shear rates and plasma viscosity. Forty male patients, ASAI-II, undergone tympanoplasty were inc...

Antibacterial Activity of Laurus nobilis: A review of literature

The presence of phenolic compounds in spices and herbs, along with the essential oils, has been gaining attention due to their various functions like antioxidant capacity, antimicrobial properties, and flavoring properti...

Investigation of GREMLIN 1, COL15A1 immunoreactivity and the relationship between microvessel density and GREMLIN 1 in papillary renal cell carcinoma and chromophobe renal cell carcinoma

Objective: The current study aimed to investigate expressions of Gremlin 1 (GREM1) (a bone morphogenetic protein antagonist and a proangiogenic factor) and COL15A1 (Collagen type XV alpha-1, encodes the proteoglycans loc...

The effects of acupuncture on nausea and vomiting and consumption of propofol in cesarean section performed with spinal anesthesia

Objective: The incidence of hypotension is 50-60% in obstetric surgeries. The most frequent comorbid clinical case of hypotention is nausea and vomiting. In addition, the probability of vomiting and nausea is very high i...

Gastrointestinal stromal tumor mimicking such as incarcerated inguinal hernia

Gastrointestinal stromal tumors, are most common sarcoma of the gastrointestinal tract, originate from Cajal cells which are responsible for the motility of the gastrointestinal tract. This sarcoma is...

Download PDF file
  • EP ID EP520517
  • DOI 10.17546/msd.16987
  • Views 50
  • Downloads 0

How To Cite

Mehmet Aydin, Refah Sayin (2016). Peripheral neuropathy as a rare syndrome related to metronidazole usage: Metronidazole may lead to persistent neuropathy. Medical Science and Discovery, 3(5), 239-41. https://europub.co.uk/articles/-A-520517