Personalised therapy in obstructive sleep apnea

Journal Title: Journal of the Indian Medical Association - Year 2019, Vol 117, Issue 7

Abstract

Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder mainly characterised by repetitive upper airway narrowing (hypopnea) and closure (apnea) during Sleep1. This leads to intermittent hypoxia, hypercapnia and frequent cortical arousals. Untreated OSA can adversely affect the cardiovascular system, neuro cognitive impairment, daytime sleepiness, and increase the risk for motor vehicle accidents2-5. Traditional therapy mainly targets anatomical problem irrespective of aetiology But this one size fit all approach is not effective in all patients and there is need to identify specify phenotype and accordingly treatment which is called personalised treatment. But still these phenotypes are not fully characterised.

Authors and Affiliations

Deependra Kumar Rai

Keywords

Related Articles

A comparitive study of haemodynamic responses to laryngeal mask airway insertion and endotracheal intubation

Earlier about 50 years back endotracheal intubation was considered the only proved technique of establishing a secure airway though associated with haemodynamic changes1. The aim of this comparative study was to know the...

Target-based therapies in thyroid cancer

Poor prognosis of thyroid cancer and advanced disease together with the absence of effective therapeutic measures has induced recent intensified basic and clinical research in this area. Complete total thyroidectomy is t...

Analysis of factors influencing lack of response in patients under Revised National Tuberculosis Control Programme (RNTCP) protocol

Tuberculosis (TB) is one of the most prevailing, contagious, chronic and a morbid infection. Our country has a high burden of TB. According to 2015 WHO statistics, India alone accounts to 23% of the total global incidenc...

Pregnancy in achondroplastic woman

Achondroplasia is an autosomal dominant chondrodysplasia. The defect is in the process of conversion of cartilage to bone. People with achondroplasia seldom reach 5 feet in height. Intelligence is in the normal range. Du...

Green insulin use disposal of insulin related supplies

A learned monk said — “Be wise in your actions today, so that you don’t regret tomorrow” This communication aims at creating awareness about disposal and recycling of waste that is generated in management of diabetes th...

Download PDF file
  • EP ID EP626745
  • DOI -
  • Views 136
  • Downloads 0

How To Cite

Deependra Kumar Rai (2019). Personalised therapy in obstructive sleep apnea. Journal of the Indian Medical Association, 117(7), 44-46. https://europub.co.uk/articles/-A-626745