Pertussis: treatment goals and prevention options
Journal Title: Актуальна інфектологія - Year 2018, Vol 6, Issue 1
Abstract
The article deals with the questions of rational therapy and immunoprophylaxis of pertussis. It is shown that antibiotics can suppress cough only in incubational period and at prodromal stage as a result of B.pertussis eradication. At the spasmodic stage of pertussis, the main target of therapy is prevention of hypoxia but not suppression of the cough or causative agent eradication. The article highlights importance of hyperleukocytosis as one of the therapy targets at pertussis in young children, through leukapheresis or exchange blood transfusions. One of the methods to decrease morbidity of pertussis is implementation into vaccination schedule the obligatory revaccination of older children and adults.
Authors and Affiliations
V. V. Mavrutenkov, S. A. Kramarov
Keywords
Related Articles
- EP ID EP273510
- DOI 10.22141/2312-413x.6.1.2018.125630
- Views 71
- Downloads 0
Urinary Tract Infection in Children with Neurogenic Bladder Dysfunction
Introduction. Among all the diseases of the urinary system, microbial-inflammatory lesions dominate, their prevalence is 29 per 1,000 of child population. Neurogenic bladder dysfunction leads to the chronicity and recurr...
Pathogenetic Mechanisms of Brain Damage at Neuroinfections in Children
The article presents the value of neuron-specific enolase and autoantibodies to glutamate receptor NR2A subunits as markers of ischemia and neurodestruction at acute meningitis in children. Presence of autoantibodies to...
Biological material for microslides to diagnose human infectious and parasitic diseases
The material for microscopic examination were blood, bone marrow, cerebrospinal fluid, lymph node puncture, feces, duodenal contents and bile, urine, sputum, urogenital tract secretions, tissue biopsies, smears from the...
Features of viral encephalitis in children according to the data of Kyiv Municipal Children’s Clinical Infectious Diseases Hospital in 2011–2016
A retrospective analysis of 46 cases of children who were hospitalized in Kyiv Municipal Children’s Clinical Infectious Diseases Hospital from 2011 to 2016 was carried out. The origin of encephalitis in children was anal...
Features of General Reactive Potential of the Body in Infants with BCG lymphadenitis
Objective: integrated health assessment of infants with BCG-induced regional lymphadenitis. Material and Methods. The work was carried out on the academic basis of pediatric infectious departments of Donetsk region and D...