Pharmaceutical Development and Physicochemical Evaluation of Polyherbal Gel for Diabetic Wounds
Journal Title: International Journal of Ayurveda and Pharmaceutical Chemistry - Year 2018, Vol 0, Issue 0
Abstract
Background: Diabetes is a group of metabolic disorders. Whether a patient has Type 1 or 2 Diabetes makes no difference when it comes to the factor of Diabetic wounds. More than 50% of diabetic wounds can increase the risk of amputation, if proper & fast treatment is not provided. This study is an attempt to bring ayurveda from laboratory to practice. Objectives: Development of the standard manufacturing process of polyherbal gel with selected ingredients & analysis of the study drug physico-chemically to develop its standard. Methods: Pharmaceutical development of polyherbal gel from Durva (Cynodondactylon), Nimba (Azadirachtaindica), Haridra (Curcuma longa), Daruharidra (Berberisaristata)&Yashtimadhu (Glycyrrhizaglabra) & physico – chemical analysis was done by different parameters e.g., physical appearance, pH, skin irritation test, rancidity test, homogeneity etc. Results: In terms of standardization pH of gel was ≤ 6 (acidic) which would be healthy for better recovery of wounds. The gel was homogenous, skin compatible & no rancidity seen. Conclusion: Topical applications have faster & better results than oral medications. Therefore, it was necessary to develop a safe, potent, effective & easy to use on daily basis with the longer shelf life & cost effective remedy of Ayurveda in the form of polyherbal gel.
Authors and Affiliations
Trupti Patil, Ashvini Deshmukh, Meenakshi Amrutkar
Keywords
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