PHARMACOGNOSTIC AND PHYTOCHEMICAL INVESTIGATION OF POTENTIALLY IMPORTANT PLANTS OF WESTERN GHATS, INDIA
Journal Title: International Journal of Pharmaceutical Sciences and Research (IJPSR) - Year 2019, Vol 10, Issue 6
Abstract
Objective: The Indian traditional system of medicine, namely Ayurveda and Siddha, are primarily based on the use of the whole plant or different parts of plant singly or in combination to make multifactorial formulations. The use of plant drugs, however, demands correct identification of species and the characterization of phytoconstituents. Materials and Methods: The plants reported for their wound healing property in the Western Ghats by tribal community viz. Semecarpus anacardium L. (Bibba), Argemone mexicana L. (Firangi Dhotara), Cocculus hirsutus L. (Vasanvel), Woodfordia fruticosa Kurz. (Dhatki) were identified, authenticated and processed. The plant materials were subjected to morphological and microscopical evaluations. The proximate analysis (moisture content, ash values, extractive values and foreign organic matters) of powdered drugs were carried out. The powdered plant materials were extracted by a Soxhlet extraction process using different solvents. The concentrated extracts were subjected to preliminary phytochemical investigation. Results: The Semecarpus anacardium L. shows less moisture (fruits; 8.73 ± 0.95) and high inorganic content (leaves; 17.50 ± 0.92) as compared to other powdered drugs. The Argemone mexicana L. (35.68 ± 2.92), Cocculus hirsutus L. (41.53 ± 3.08) and Woodfordia fruticosa K. (29.26 ± 1.75 and 24.06 ± 3.01) shows high extractive values in methanolic extract whereas Semecarpus anacardium L. (fruits; 34.61 ± 0.75 and leaves 37.69 ± 1.86) shows in ethanolic extract. The least foreign organic matters (0.76 ± 0.45) were found in Woodfordia fruticosa K. flowers. The alkaloids, carbohydrates, steroids, glycosides, flavonoids and phenolic compounds were found in ethanolic and methanolic extracts. Conclusion: The data thus obtained by standardization of plant materials can be used during the preparation of polyherbal formulations to increase stability and efficacy.
Authors and Affiliations
S. R. Wayal et al.
BIOSYNTHESIS AND CHARACTERIZATION OF GOLD NANOPARTICLE FROM COCCINIA GRANDIS AND ITS CATALYTIC ACTIVITY
The fabrication of spherical gold nanoparticles (AuNPs) using the reducing agent and stabilizing agent Coccinia grandis is reported here. Irradiation of the reaction mixture under a domestic microwave oven enabled the fo...
EFFECT OF STEROL ISOLATE FROM ECHINODERM STELLASTER EQUESTRIS ON ZEBRAFISH (DANIO RERIO)
Expansion of secondary metabolites from marine resources mainly from echinoderms has been a subject of intense research due to massive bioactive nature. Isolation of new secondary metabolites from sea stars has been foun...
QUALITY BY DESIGN: CHANGING OUTLOOK OF PHARMACEUTICAL DEVELOPMENT
The concept of quality by design (QbD) justifies the saying that, quality is not an act, it is a habit. This innovative and systematic approach to pharmaceutical development based on scientific principles has been a brea...
THE EFFECT OF MEDIA AND FERMENTATION CONDITION TOWARD ANTIBACTERIAL ACTIVITIES OF BACILLUS SP. DA11 ASSOCIATED WITH SARCOPHYTON SP.
The emergence of antibiotic-multidrug resistant microorganisms is an essential issue in the health sector. Consequently, the exploration of new antimicrobial compounds from many promising resources is urgently required....
A QUEST FOR BETTER PROBIOTIC DELIVERY AND FRONTIERS OF PROBIOTIC APPLICATION IN MEDICAL SCIENCE: A CRITICAL REVIEW
Probiotics are live microorganisms that when introduced orally positively contribute to the activity of the intestinal microflora and the health of its host. Various studies showed that probiotics are potentially able to...