Pharmacognostical, Phytochemical, Antioxidant and Antimicrobial Activity of Costus woodsonii
Journal Title: Edelweiss Applied Science and Technology - Year 2019, Vol 3, Issue 1
Abstract
Background: Herbal medicine mostly contains wide range of chemical compounds responsible for medicinal therapeutic use. Costus woodsonii is commonly called as Red Button Ginger and synonyms of the botanical name are Costus spiralis, Alpinia spiralis and Costus pisonis. In Malay, it is known as Setawar Halia Merah. In Chinese, it is known as Hong Bi Qiao Jiang. Objective: This research was conducted to study the pharmacognostical, phytochemical, antioxidant and antimicrobial activity of C. woodsonii leaf extracts. Method: Macroscopy, microscopy, phytochemical analysis, thin layer chromatography, antioxidant activity and antimicrobial activity of C. woodsonii leaf were carried out. Total flavonoids were estimated in the leaf extract. The total phenolic content of C. woodsonii leaf was determined using Folin-Ciocalteu reagent. The antioxidant activity of leaf extract of C. woodsonii was determined by performing DPPH radical scavenging. The microbial activity was determined by Well diffusion test, MIC (Minimum Inhibitory Concentration) test and MBC (Minimum Bactericidal Concentration) test. Result and Discussion: C. woodsonii belongs to costaceae with elliptical green leaves. Till now are no extensive studies on C. woodsonii. Preliminary phytochemical analysis revealed the presence of flavonoid, steroid, fat, phenol, tannin and mucilage in leaf extract. Physicochemical studies further revealed the ash value of leaf as 8.7%. Among the three extractions, alcohol extractive values showed the highest as 13%. Loss on drying at 105 degree Celsius in leaf was found to be 12.67%. The plant extract showed total phenolic content of 7.941 mg GAE/g at concentration of 5µg/ml. As for flavonoids content, plant extract showed 21.7 mg RE/g at concentration of 200µg/ml and 43.4 mg RE/g at concentration of 400µg/ml. For antioxidant activity, the plant extract showed weak antioxidant activity in DPPH scavenging activity assay. For antimicrobial test, the leaf extract of C. woodsonii showed weak antimicrobial activity. Conclusion: From this study, it can conclude that C. woodsonii leaf extract possess weak antioxidant activity and weak antimicrobial activity which need to be further validated by using more antioxidant assays and antimicrobial tests.
Authors and Affiliations
Sikarwar MS, Szeek CK and Paliwal N
Keywords
Related Articles
- EP ID EP678505
- DOI https://doi.org/10.33805/2576-8484.168
- Views 181
- Downloads 0
The Bio Immune(G)ene Medicine or How to Use a Maximum of Molecular Resources of the Cell for Therapeutic Purposes
At a time when emerging concepts capable of revolutionizing old medical paradigms are flourishing, such as systems biology, integrative medicine or personalized medicine, it is of the utmost interest to observe how such...
Ozone Layer Depletion and Climate Change in Nigeria: Problems and Prospects-A Review
Nigerians are facing a serious global environmental problem and there is a widespread concern that the ozone layer which is bringing out terrible deterioration thus contributes to climatic change and global warming. This...
Antioxidative Potential of Garlic on Lead-Induced Oxidative Stress and Effect on Enzyme Activity in Rice Plants
Seedling of Ofada rice (Oryza sativum L) were raised in sand (swampy) and clay (upland) cultures under 500mg/kg lead acetate and 500mg/kg garlic aqueous extract for 40-days. The uptake and distribution pattern of lead wi...
Design and Analysis of Ultrasonic Horns Operating in Multiple Vibration Modes
A number of recent studies have shown that combining different modal responses can provide opportunities to improve the vibration behavior of the output faces of tuned ultrasonic horns to provide a more effective use of...
Role of Cadmium and Lead in Nephrotoxicity
Nephrotoxicity stands amongst the most widely recognized kidney issues and happens when human body is presented to a medication or toxins that give harm to kidneys. At the point when kidney harm happens, patient cannot f...