Pharmacological aptitude and profiling of active constituent from Otostegia limbata-Comprehensive review
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2016, Vol 6, Issue 11
Abstract
The plants provide medicinally valuable substances since ancient time and are the cheapest, oldest, as well as imperative source of pharmacologically active chemical compounds used for the treatment of several diseases. Medicinally, Otostegia limbata (O. limbata) is very imperative species of genus Otostegia which are extensively utilized by traditional practitioners against several ailments and its chemical constituents possess antispasmodic, antiulcer, antidepressant, sedative, anxiolytic, anti-inflammatory for eyes inflammation, antibacterial, antioxidant, haemagglutination activity, cholinesterase inhibition for Alzheimer’s treatment, antitussive potential, anti-aphids and larvicidal potential aptitude. The pharmacological impact of O. limbata and their diverse biological activities along with its active constituent are complied in this review. This species provide rich variety of biologically active secondary metabolites. Quite large number of active compounds isolated from O. limbata is the evidence to have considerable potential making them competent candidate for critically required novel drugs.
Evaluation of antimicrobial study in in vitro application of Clerodendrum infortunatum Linn.
Objective: To evaluate the antimicrobial potency of ethanol and chloroform extracts of root, leaf and stem of Clerodendrum infortunatum (Verbenaceae) and to explore a scientific data as this plant was randomly use in tra...
In vitro antioxidant activities and HPTLC analysis of ethanolic extract of Cayratia trifolia (L.)
Objective: To assess the preliminary phytochemical constituents, free radical scavenging activities and HPTLC analysis of the whole plant of the ethanolic extract of Cayratia trifolia. Methods: 2, 2- diphenyl-1-picryl-hy...
Anxiolytic effect ofOxalis corniculata (Oxalidaceae) in mice
Objective: To investigate the anxiolytic effect of Oxalis corniculata in mice was examined. Methods: The open field test, elevated plus maze test and anti-fighting test were used to assess the anxiolytic activity of etha...
A rare cause of cellulitis (necrotic arachnidism): a report of two cases
Bites from brown recluse spiders (Loxosceles reclusa) result in several clinical manifestations, causing painful, disfiguring necrotic ulcers and, uncommonly, severe systemic effects. We report two cases reports with nec...
Histopathology of mammary gland in Staphylococcus aureus induced mastitis in mice
Objective: To investigate the histopathological changes of mouse mammary tissue damage in dose and durational pathogenicity of Staphylococcus aureus (S. aureus) inoculums. Methods: The minimal tissue inflammation dose of...